Lichen planus pemphigoides: A unique form of bullous and lichenoid eruptions secondary to nivolumab

The widespread use of PD‐1 inhibitors to treat various solid tumors has brought certain challenges for the clinician, including immune‐related adverse events (irAEs). Cutaneous toxicities are among the most observed irAEs. Bullous and lichenoid dermatoses following PD‐1 inhibitor therapy have been d...

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Autores principales: Shah, Rohan R., Bhate, Chinmoy, Hernandez, Amanda, Ho, Chin Hung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Review Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9286841/
https://www.ncbi.nlm.nih.gov/pubmed/35266258
http://dx.doi.org/10.1111/dth.15432
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author Shah, Rohan R.
Bhate, Chinmoy
Hernandez, Amanda
Ho, Chin Hung
author_facet Shah, Rohan R.
Bhate, Chinmoy
Hernandez, Amanda
Ho, Chin Hung
author_sort Shah, Rohan R.
collection PubMed
description The widespread use of PD‐1 inhibitors to treat various solid tumors has brought certain challenges for the clinician, including immune‐related adverse events (irAEs). Cutaneous toxicities are among the most observed irAEs. Bullous and lichenoid dermatoses following PD‐1 inhibitor therapy have been described. Here we report a novel case of lichen planus pemphigoides, featuring characteristics of both bullous pemphigoid and lichen planus, in a patient treated with nivolumab for renal cell carcinoma. We subsequently review all three cutaneous conditions which may arise in the context of PD‐1 inhibitor therapy.
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spelling pubmed-92868412022-07-19 Lichen planus pemphigoides: A unique form of bullous and lichenoid eruptions secondary to nivolumab Shah, Rohan R. Bhate, Chinmoy Hernandez, Amanda Ho, Chin Hung Dermatol Ther Review Articles The widespread use of PD‐1 inhibitors to treat various solid tumors has brought certain challenges for the clinician, including immune‐related adverse events (irAEs). Cutaneous toxicities are among the most observed irAEs. Bullous and lichenoid dermatoses following PD‐1 inhibitor therapy have been described. Here we report a novel case of lichen planus pemphigoides, featuring characteristics of both bullous pemphigoid and lichen planus, in a patient treated with nivolumab for renal cell carcinoma. We subsequently review all three cutaneous conditions which may arise in the context of PD‐1 inhibitor therapy. John Wiley & Sons, Inc. 2022-03-15 2022-05 /pmc/articles/PMC9286841/ /pubmed/35266258 http://dx.doi.org/10.1111/dth.15432 Text en © 2022 The Authors. Dermatologic Therapy published by Wiley Periodicals LLC. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Articles
Shah, Rohan R.
Bhate, Chinmoy
Hernandez, Amanda
Ho, Chin Hung
Lichen planus pemphigoides: A unique form of bullous and lichenoid eruptions secondary to nivolumab
title Lichen planus pemphigoides: A unique form of bullous and lichenoid eruptions secondary to nivolumab
title_full Lichen planus pemphigoides: A unique form of bullous and lichenoid eruptions secondary to nivolumab
title_fullStr Lichen planus pemphigoides: A unique form of bullous and lichenoid eruptions secondary to nivolumab
title_full_unstemmed Lichen planus pemphigoides: A unique form of bullous and lichenoid eruptions secondary to nivolumab
title_short Lichen planus pemphigoides: A unique form of bullous and lichenoid eruptions secondary to nivolumab
title_sort lichen planus pemphigoides: a unique form of bullous and lichenoid eruptions secondary to nivolumab
topic Review Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9286841/
https://www.ncbi.nlm.nih.gov/pubmed/35266258
http://dx.doi.org/10.1111/dth.15432
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