Crosstalk between Lipid Rafts and Aging: New Frontiers for Delaying Aging

With the rapid aging in the global population, delay of aging has become a hot research topic. Lipid rafts (LRs) are microdomains in the plasma membrane that contain sphingolipids and cholesterol. Emerging evidence indicates an interesting interplay between LRs and aging. LRs and their components ar...

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Detalles Bibliográficos
Autores principales: Zhang, Shuo, Zhu, Neng, Gu, Jia, Li, Hong-Fang, Qiu, Yun, Liao, Duan-Fang, Qin, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JKL International LLC 2022
Materias:
Opinion
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9286918/
https://www.ncbi.nlm.nih.gov/pubmed/35855333
http://dx.doi.org/10.14336/AD.2022.0116
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author Zhang, Shuo
Zhu, Neng
Gu, Jia
Li, Hong-Fang
Qiu, Yun
Liao, Duan-Fang
Qin, Li
author_facet Zhang, Shuo
Zhu, Neng
Gu, Jia
Li, Hong-Fang
Qiu, Yun
Liao, Duan-Fang
Qin, Li
author_sort Zhang, Shuo
collection PubMed
description With the rapid aging in the global population, delay of aging has become a hot research topic. Lipid rafts (LRs) are microdomains in the plasma membrane that contain sphingolipids and cholesterol. Emerging evidence indicates an interesting interplay between LRs and aging. LRs and their components are altered with aging. Further, the aging process is strongly influenced by LRs. In recent years, LRs and their component signaling molecules have been recognized to affect aging by interfering with its hallmarks. Therefore, targeting LRs is a promising strategy to delay aging.
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spelling pubmed-92869182022-07-18 Crosstalk between Lipid Rafts and Aging: New Frontiers for Delaying Aging Zhang, Shuo Zhu, Neng Gu, Jia Li, Hong-Fang Qiu, Yun Liao, Duan-Fang Qin, Li Aging Dis Opinion With the rapid aging in the global population, delay of aging has become a hot research topic. Lipid rafts (LRs) are microdomains in the plasma membrane that contain sphingolipids and cholesterol. Emerging evidence indicates an interesting interplay between LRs and aging. LRs and their components are altered with aging. Further, the aging process is strongly influenced by LRs. In recent years, LRs and their component signaling molecules have been recognized to affect aging by interfering with its hallmarks. Therefore, targeting LRs is a promising strategy to delay aging. JKL International LLC 2022-07-11 /pmc/articles/PMC9286918/ /pubmed/35855333 http://dx.doi.org/10.14336/AD.2022.0116 Text en copyright: © 2022 Zhang et al. https://creativecommons.org/licenses/by/2.0/this is an open access article distributed under the terms of the creative commons attribution license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.
spellingShingle Opinion
Zhang, Shuo
Zhu, Neng
Gu, Jia
Li, Hong-Fang
Qiu, Yun
Liao, Duan-Fang
Qin, Li
Crosstalk between Lipid Rafts and Aging: New Frontiers for Delaying Aging
title Crosstalk between Lipid Rafts and Aging: New Frontiers for Delaying Aging
title_full Crosstalk between Lipid Rafts and Aging: New Frontiers for Delaying Aging
title_fullStr Crosstalk between Lipid Rafts and Aging: New Frontiers for Delaying Aging
title_full_unstemmed Crosstalk between Lipid Rafts and Aging: New Frontiers for Delaying Aging
title_short Crosstalk between Lipid Rafts and Aging: New Frontiers for Delaying Aging
title_sort crosstalk between lipid rafts and aging: new frontiers for delaying aging
topic Opinion
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9286918/
https://www.ncbi.nlm.nih.gov/pubmed/35855333
http://dx.doi.org/10.14336/AD.2022.0116
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