HAO1-mediated oxalate metabolism promotes lung pre-metastatic niche formation by inducing neutrophil extracellular traps

Metabolic reprogramming has been shown to be involved in cancer-induced pre-metastatic niche (PMN) formation, but the underlying mechanisms have been insufficiently explored. Here, we showed that hydroxyacid oxidase 1 (HAO1), a rate-limiting enzyme of oxalate synthesis, was upregulated in the alveol...

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Detalles Bibliográficos
Autores principales: Zeng, Zhicheng, Xu, Shaowan, Wang, Feifei, Peng, Xin, Zhang, Wanning, Zhan, Yizhi, Ding, Yanqing, Liu, Ziguang, Liang, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9287177/
https://www.ncbi.nlm.nih.gov/pubmed/35739335
http://dx.doi.org/10.1038/s41388-022-02248-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9287177/
https://www.ncbi.nlm.nih.gov/pubmed/35739335
http://dx.doi.org/10.1038/s41388-022-02248-3

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