A GC–MS-based untargeted metabolomics approach for comprehensive metabolic profiling of vancomycin-induced toxicity in mice

BACKGROUND: Vancomycin is a glycopeptide antibiotic that is commonly used for severe drug-resistant infections treatment. Application of vancomycin frequently leads to severe ototoxicity, hepatotoxicity, and nephrotoxicity; however, the comprehensive metabolic analysis of vancomycin-induced toxicity...

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Detalles Bibliográficos
Autores principales: Cui, Changmeng, Zhu, Li, Wang, Qian, Liu, Ruijuan, Xie, Dadi, Guo, Yujin, Yu, Dingyi, Wang, Changshui, Chen, Dan, Jiang, Pei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9287194/
https://www.ncbi.nlm.nih.gov/pubmed/35855991
http://dx.doi.org/10.1016/j.heliyon.2022.e09869

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