Fine-tuned KDM1A alternative splicing regulates human cardiomyogenesis through an enzymatic-independent mechanism

The histone demethylase KDM1A is a multi-faceted regulator of vital developmental processes, including mesodermal and cardiac tube formation during gastrulation. However, it is unknown whether the fine-tuning of KDM1A splicing isoforms, already shown to regulate neuronal maturation, is crucial for t...

Descripción completa

Detalles Bibliográficos
Autores principales: Astro, Veronica, Ramirez-Calderon, Gustavo, Pennucci, Roberta, Caroli, Jonatan, Saera-Vila, Alfonso, Cardona-Londoño, Kelly, Forastieri, Chiara, Fiacco, Elisabetta, Maksoud, Fatima, Alowaysi, Maryam, Sogne, Elisa, Falqui, Andrea, Gonzàlez, Federico, Montserrat, Nuria, Battaglioli, Elena, Mattevi, Andrea, Adamo, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9287196/
https://www.ncbi.nlm.nih.gov/pubmed/35856020
http://dx.doi.org/10.1016/j.isci.2022.104665

Ejemplares similares

Ejemplares similares