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Orbital Myositis in a Patient With Ileal Crohn's Disease in Remission on Vedolizumab

Orbital myositis (OM) is an extremely rare ocular extraintestinal manifestation of inflammatory bowel disease. Acute or chronic inflammation of one or more extraocular muscles leads to symptoms related to the mass effect including orbital pain, swelling, ophthalmoplegia, proptosis, and diplopia. Alt...

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Detalles Bibliográficos
Autores principales: Sandhu, Sunny, Wang, Timothy, Donet, Jean A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9287271/
https://www.ncbi.nlm.nih.gov/pubmed/35919668
http://dx.doi.org/10.14309/crj.0000000000000775
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author Sandhu, Sunny
Wang, Timothy
Donet, Jean A.
author_facet Sandhu, Sunny
Wang, Timothy
Donet, Jean A.
author_sort Sandhu, Sunny
collection PubMed
description Orbital myositis (OM) is an extremely rare ocular extraintestinal manifestation of inflammatory bowel disease. Acute or chronic inflammation of one or more extraocular muscles leads to symptoms related to the mass effect including orbital pain, swelling, ophthalmoplegia, proptosis, and diplopia. Although the use of steroids typically leads to rapid resolution of symptoms, recurrence is common, necessitating long-term steroid-sparing therapies. Given the rare presentation of OM, its pathogenesis and optimal therapy are not well established. We present a young woman with Crohn's disease in remission on vedolizumab who developed OM, and we discuss our management approach.
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spelling pubmed-92872712022-08-01 Orbital Myositis in a Patient With Ileal Crohn's Disease in Remission on Vedolizumab Sandhu, Sunny Wang, Timothy Donet, Jean A. ACG Case Rep J Case Report Orbital myositis (OM) is an extremely rare ocular extraintestinal manifestation of inflammatory bowel disease. Acute or chronic inflammation of one or more extraocular muscles leads to symptoms related to the mass effect including orbital pain, swelling, ophthalmoplegia, proptosis, and diplopia. Although the use of steroids typically leads to rapid resolution of symptoms, recurrence is common, necessitating long-term steroid-sparing therapies. Given the rare presentation of OM, its pathogenesis and optimal therapy are not well established. We present a young woman with Crohn's disease in remission on vedolizumab who developed OM, and we discuss our management approach. Wolters Kluwer 2022-05-12 /pmc/articles/PMC9287271/ /pubmed/35919668 http://dx.doi.org/10.14309/crj.0000000000000775 Text en © 2022 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of The American College of Gastroenterology. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND) (https://creativecommons.org/licenses/by-nc-nd/4.0/) , where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.
spellingShingle Case Report
Sandhu, Sunny
Wang, Timothy
Donet, Jean A.
Orbital Myositis in a Patient With Ileal Crohn's Disease in Remission on Vedolizumab
title Orbital Myositis in a Patient With Ileal Crohn's Disease in Remission on Vedolizumab
title_full Orbital Myositis in a Patient With Ileal Crohn's Disease in Remission on Vedolizumab
title_fullStr Orbital Myositis in a Patient With Ileal Crohn's Disease in Remission on Vedolizumab
title_full_unstemmed Orbital Myositis in a Patient With Ileal Crohn's Disease in Remission on Vedolizumab
title_short Orbital Myositis in a Patient With Ileal Crohn's Disease in Remission on Vedolizumab
title_sort orbital myositis in a patient with ileal crohn's disease in remission on vedolizumab
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9287271/
https://www.ncbi.nlm.nih.gov/pubmed/35919668
http://dx.doi.org/10.14309/crj.0000000000000775
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