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iCodon customizes gene expression based on the codon composition

Messenger RNA (mRNA) stability substantially impacts steady-state gene expression levels in a cell. mRNA stability is strongly affected by codon composition in a translation-dependent manner across species, through a mechanism termed codon optimality. We have developed iCodon (www.iCodon.org), an al...

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Detalles Bibliográficos
Autores principales:	Diez, Michay, Medina-Muñoz, Santiago Gerardo, Castellano, Luciana Andrea, da Silva Pescador, Gabriel, Wu, Qiushuang, Bazzini, Ariel Alejandro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9287306/ https://www.ncbi.nlm.nih.gov/pubmed/35840631 http://dx.doi.org/10.1038/s41598-022-15526-7

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