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Insulin-like growth factor 1 receptor mediates photoreceptor neuroprotection
Insulin-like growth factor I (IGF-1) is a neurotrophic factor and is the ligand for insulin-like growth factor 1 receptor (IGF-1R). Reduced expression of IGF-1 has been reported to cause deafness, mental retardation, postnatal growth failure, and microcephaly. IGF-1R is expressed in the retina and p...
Autores principales: | Rajala, Ammaji, Teel, Kenneth, Bhat, Mohd A., Batushansky, Albert, Griffin, Timothy M., Purcell, Lindsey, Rajala, Raju V. S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9287313/ https://www.ncbi.nlm.nih.gov/pubmed/35840554 http://dx.doi.org/10.1038/s41419-022-05074-3 |
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