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Efficient spatially targeted gene editing using a near-infrared activatable protein-conjugated nanoparticle for brain applications

Spatial control of gene expression is critical to modulate cellular functions and deconstruct the function of individual genes in biological processes. Light-responsive gene-editing formulations have been recently developed; however, they have shown limited applicability in vivo due to poor tissue p...

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Detalles Bibliográficos
Autores principales: Rebelo, Catarina, Reis, Tiago, Guedes, Joana, Saraiva, Cláudia, Rodrigues, Artur Filipe, Simões, Susana, Bernardino, Liliana, Peça, João, Pinho, Sónia L. C., Ferreira, Lino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9287341/
https://www.ncbi.nlm.nih.gov/pubmed/35840564
http://dx.doi.org/10.1038/s41467-022-31791-6

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