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Efficient spatially targeted gene editing using a near-infrared activatable protein-conjugated nanoparticle for brain applications
Spatial control of gene expression is critical to modulate cellular functions and deconstruct the function of individual genes in biological processes. Light-responsive gene-editing formulations have been recently developed; however, they have shown limited applicability in vivo due to poor tissue p...
Autores principales: | Rebelo, Catarina, Reis, Tiago, Guedes, Joana, Saraiva, Cláudia, Rodrigues, Artur Filipe, Simões, Susana, Bernardino, Liliana, Peça, João, Pinho, Sónia L. C., Ferreira, Lino |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9287341/ https://www.ncbi.nlm.nih.gov/pubmed/35840564 http://dx.doi.org/10.1038/s41467-022-31791-6 |
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