Adipocyte-specific ablation of the Ca(2+) pump SERCA2 impairs whole-body metabolic function and reveals the diverse metabolic flexibility of white and brown adipose tissue

OBJECTIVE: Sarco/endoplasmic reticulum Ca(2+)-ATPase (SERCA) transports Ca(2+) from the cytosol into the endoplasmic retitculum (ER) and is essential for appropriate regulation of intracellular Ca(2+) homeostasis. The objective of this study was to test the hypothesis that SERCA pumps are involved i...

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Detalles Bibliográficos
Autores principales: Bauzá-Thorbrügge, Marco, Banke, Elin, Chanclón, Belén, Peris, Eduard, Wu, Yanling, Musovic, Saliha, Jönsson, Cecilia, Strålfors, Peter, Rorsman, Patrik, Olofsson, Charlotta S., Wernstedt Asterholm, Ingrid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9287368/
https://www.ncbi.nlm.nih.gov/pubmed/35760318
http://dx.doi.org/10.1016/j.molmet.2022.101535

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