Structure-based rational design of an enhanced fluorogen-activating protein for fluorogens based on GFP chromophore

“Fluorescence-Activating and absorption-Shifting Tag” (FAST) is a well-studied fluorogen-activating protein with high brightness and low size, able to activate a wide range of fluorogens. This makes FAST a promising target for both protein and fluorogen optimization. Here, we describe the structure-...

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Detalles Bibliográficos
Autores principales: Goncharuk, Marina V., Baleeva, Nadezhda S., Nolde, Dmitry E., Gavrikov, Alexey S., Mishin, Alexey V., Mishin, Alexander S., Sosorev, Andrey Y., Arseniev, Alexander S., Goncharuk, Sergey A., Borshchevskiy, Valentin I., Efremov, Roman G., Mineev, Konstantin S., Baranov, Mikhail S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9287381/
https://www.ncbi.nlm.nih.gov/pubmed/35840781
http://dx.doi.org/10.1038/s42003-022-03662-9

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