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Timing is everything: structural insights into the disease-linked Kv3 channels controlling fast action-potential firing in the brain

Kv3 channels enable neurons to fire at very high frequencies (>100 Hz) which is fundamental to brain development and our ability to make sense of the world at large. Cryo-EM and structure-function studies by Chi et al. now uncover Kv3 channel gating mechanisms and support new precision medicine a...

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Detalles Bibliográficos
Autor principal:	Gunthorpe, Martin J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Comment
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9287389/ https://www.ncbi.nlm.nih.gov/pubmed/35840565 http://dx.doi.org/10.1038/s41467-022-31537-4

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