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Spatial organization of hydrophobic and charged residues affects protein thermal stability and binding affinity
What are the molecular determinants of protein–protein binding affinity and whether they are similar to those regulating fold stability are two major questions of molecular biology, whose answers bring important implications both from a theoretical and applicative point of view. Here, we analyze che...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9287411/ https://www.ncbi.nlm.nih.gov/pubmed/35840609 http://dx.doi.org/10.1038/s41598-022-16338-5 |