Cutaneous and acral melanoma cross-OMICs reveals prognostic cancer drivers associated with pathobiology and ultraviolet exposure

Ultraviolet radiation (UV) is causally linked to cutaneous melanoma, yet the underlying epigenetic mechanisms, known as molecular sensors of exposure, have not been characterized in clinical biospecimens. Here, we integrate clinical, epigenome (DNA methylome), genome and transcriptome profiling of 1...

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Detalles Bibliográficos
Autores principales: Vicente, Anna Luiza Silva Almeida, Novoloaca, Alexei, Cahais, Vincent, Awada, Zainab, Cuenin, Cyrille, Spitz, Natália, Carvalho, André Lopes, Evangelista, Adriane Feijó, Crovador, Camila Souza, Reis, Rui Manuel, Herceg, Zdenko, de Lima Vazquez, Vinicius, Ghantous, Akram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9287446/
https://www.ncbi.nlm.nih.gov/pubmed/35840550
http://dx.doi.org/10.1038/s41467-022-31488-w

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