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New-onset psychosis following COVID-19 infection in a patient with no psychiatric history: A longitudinal case report
BACKGROUND: Viral infection, including COVID-19, has been implicated as a potential cause of various neurobehavioral issues. An increasing number of case reports suggest that current or recent COVID-19 infection may cause new onset of psychotic symptoms in some individuals, potentially related to vi...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Published by Elsevier B.V.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9287465/ https://www.ncbi.nlm.nih.gov/pubmed/36457730 http://dx.doi.org/10.1016/j.psycr.2022.100035 |
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author | Runyan, Matthew Fawver, Jay Coupe, Amanda Drouin, Michelle |
author_facet | Runyan, Matthew Fawver, Jay Coupe, Amanda Drouin, Michelle |
author_sort | Runyan, Matthew |
collection | PubMed |
description | BACKGROUND: Viral infection, including COVID-19, has been implicated as a potential cause of various neurobehavioral issues. An increasing number of case reports suggest that current or recent COVID-19 infection may cause new onset of psychotic symptoms in some individuals, potentially related to viral inflammation or infection of the nervous system. CASE PRESENTATION: A 26-year-old woman with no psychiatric history presented with severe psychotic symptoms days after recovery from a mild COVID-19 infection. No other etiologies for psychosis were identified via diagnostic testing, review of medical history, or interviews with family. Her symptoms persisted for approximately two months, requiring three inpatient admissions, various medication trials, and ongoing outpatient follow-up. With continued use of quetiapine and lithium, she returned to living independently and working full-time, and discontinued all medication approximately nine months after symptom onset. CONCLUSION: The psychiatric and cognitive effects of COVID-19 infection are not yet fully understood. Given the widespread and ongoing nature of this pandemic, this remains an important focus of further investigation, especially within the context of potential long-term complications. |
format | Online Article Text |
id | pubmed-9287465 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Published by Elsevier B.V. |
record_format | MEDLINE/PubMed |
spelling | pubmed-92874652022-07-18 New-onset psychosis following COVID-19 infection in a patient with no psychiatric history: A longitudinal case report Runyan, Matthew Fawver, Jay Coupe, Amanda Drouin, Michelle Psychiatry Res Case Rep Article BACKGROUND: Viral infection, including COVID-19, has been implicated as a potential cause of various neurobehavioral issues. An increasing number of case reports suggest that current or recent COVID-19 infection may cause new onset of psychotic symptoms in some individuals, potentially related to viral inflammation or infection of the nervous system. CASE PRESENTATION: A 26-year-old woman with no psychiatric history presented with severe psychotic symptoms days after recovery from a mild COVID-19 infection. No other etiologies for psychosis were identified via diagnostic testing, review of medical history, or interviews with family. Her symptoms persisted for approximately two months, requiring three inpatient admissions, various medication trials, and ongoing outpatient follow-up. With continued use of quetiapine and lithium, she returned to living independently and working full-time, and discontinued all medication approximately nine months after symptom onset. CONCLUSION: The psychiatric and cognitive effects of COVID-19 infection are not yet fully understood. Given the widespread and ongoing nature of this pandemic, this remains an important focus of further investigation, especially within the context of potential long-term complications. Published by Elsevier B.V. 2022-12 2022-07-16 /pmc/articles/PMC9287465/ /pubmed/36457730 http://dx.doi.org/10.1016/j.psycr.2022.100035 Text en © 2022 Published by Elsevier B.V. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Article Runyan, Matthew Fawver, Jay Coupe, Amanda Drouin, Michelle New-onset psychosis following COVID-19 infection in a patient with no psychiatric history: A longitudinal case report |
title | New-onset psychosis following COVID-19 infection in a patient with no psychiatric history: A longitudinal case report |
title_full | New-onset psychosis following COVID-19 infection in a patient with no psychiatric history: A longitudinal case report |
title_fullStr | New-onset psychosis following COVID-19 infection in a patient with no psychiatric history: A longitudinal case report |
title_full_unstemmed | New-onset psychosis following COVID-19 infection in a patient with no psychiatric history: A longitudinal case report |
title_short | New-onset psychosis following COVID-19 infection in a patient with no psychiatric history: A longitudinal case report |
title_sort | new-onset psychosis following covid-19 infection in a patient with no psychiatric history: a longitudinal case report |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9287465/ https://www.ncbi.nlm.nih.gov/pubmed/36457730 http://dx.doi.org/10.1016/j.psycr.2022.100035 |
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