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MiR-203 is an anti-obese microRNA by targeting apical sodium-dependent bile acid transporter
Obesity is characterized by excessive fat deposition within the body. Bile acids (BA) are important regulators for controlling the absorption of lipid. Here we show that miR-203 exerts weight-loss and lipid-lowering effects by increasing total BA excretion in obese rodents. miR-203 overexpression tr...
Autores principales: | Liu, Xin, Cheng, Feiran, Bai, Xue, Zhao, Tong, Zhao, Limin, Wang, Lei, Li, Mingqi, Wu, Xianxian, Chen, Xiaohui, Tang, Pingping, Wang, Mengxue, Jiang, Lintong, Yan, Chaoqi, Pei, Fenghua, Gao, Xu, Ma, Ning, Yang, Baofeng, Zhang, Yong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9287609/ https://www.ncbi.nlm.nih.gov/pubmed/35856025 http://dx.doi.org/10.1016/j.isci.2022.104708 |
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