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The effects of nitrate ingestion on high-intensity endurance time-trial performance: A systematic review and meta-analysis

BACKGROUND/OBJECTIVE: Dietary nitrate ingestion extends endurance capacity, but data supporting endurance time-trial performance are unclear. This systematic review and meta-analysis evaluated the evidence for dietary nitrate supplementation to improve high-intensity endurance time-trial performance...

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Autores principales: Wong, Tak Hiong, Sim, Alexiaa, Burns, Stephen F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Society of Chinese Scholars on Exercise Physiology and Fitness 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9287610/
https://www.ncbi.nlm.nih.gov/pubmed/35892115
http://dx.doi.org/10.1016/j.jesf.2022.06.004
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author Wong, Tak Hiong
Sim, Alexiaa
Burns, Stephen F.
author_facet Wong, Tak Hiong
Sim, Alexiaa
Burns, Stephen F.
author_sort Wong, Tak Hiong
collection PubMed
description BACKGROUND/OBJECTIVE: Dietary nitrate ingestion extends endurance capacity, but data supporting endurance time-trial performance are unclear. This systematic review and meta-analysis evaluated the evidence for dietary nitrate supplementation to improve high-intensity endurance time-trial performance over 5–30 min on the premise that nitrate may alleviate peripheral fatigue over shorter durations. METHODS: A systematic literature search and data extraction was carried out following PRISMA guidelines and the PICOS framework within five databases: PubMed, ProQuest, ScienceDirect, Scopus and SPORTDiscus. Search terms used were: (nitrate OR nitrite OR beetroot) AND (high intensity OR all out) AND (time trial or total work done) AND performance. RESULTS: Twenty-four studies were included. Fifteen studies applied an acute supplementation strategy (4.1 mmol–15.2 mmol serving on one day), eight chronic supplementation (4.0 mmol–13.0 mmol per day over 3–15 days), and one applied both acute and chronic supplementation (8.0 mmol on one day and over 15 days). Standardised mean difference for time-trial ranging from 5 to 30 min showed an overall trivial effect in favour of nitrate (Hedges'g = 0.15, 95% CI -0.00 to 0.31, Z = 1.95, p = 0.05). Subgroup analysis revealed a small, borderline effect in favour of chronic nitrate intervention (Hedges'g = 0.30, 95% CI -0.00 to 0.59, Z = 1.94, p = 0.05), and a non-significant effect for acute nitrate intervention (Hedges'g = 0.10, 95% CI -0.08 to 0.28, Z = 1.11, p = 0.27). CONCLUSION: Chronic nitrate supplementation improves time-trial performance ranging from 5 to 30 min.
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spelling pubmed-92876102022-07-25 The effects of nitrate ingestion on high-intensity endurance time-trial performance: A systematic review and meta-analysis Wong, Tak Hiong Sim, Alexiaa Burns, Stephen F. J Exerc Sci Fit Review Article BACKGROUND/OBJECTIVE: Dietary nitrate ingestion extends endurance capacity, but data supporting endurance time-trial performance are unclear. This systematic review and meta-analysis evaluated the evidence for dietary nitrate supplementation to improve high-intensity endurance time-trial performance over 5–30 min on the premise that nitrate may alleviate peripheral fatigue over shorter durations. METHODS: A systematic literature search and data extraction was carried out following PRISMA guidelines and the PICOS framework within five databases: PubMed, ProQuest, ScienceDirect, Scopus and SPORTDiscus. Search terms used were: (nitrate OR nitrite OR beetroot) AND (high intensity OR all out) AND (time trial or total work done) AND performance. RESULTS: Twenty-four studies were included. Fifteen studies applied an acute supplementation strategy (4.1 mmol–15.2 mmol serving on one day), eight chronic supplementation (4.0 mmol–13.0 mmol per day over 3–15 days), and one applied both acute and chronic supplementation (8.0 mmol on one day and over 15 days). Standardised mean difference for time-trial ranging from 5 to 30 min showed an overall trivial effect in favour of nitrate (Hedges'g = 0.15, 95% CI -0.00 to 0.31, Z = 1.95, p = 0.05). Subgroup analysis revealed a small, borderline effect in favour of chronic nitrate intervention (Hedges'g = 0.30, 95% CI -0.00 to 0.59, Z = 1.94, p = 0.05), and a non-significant effect for acute nitrate intervention (Hedges'g = 0.10, 95% CI -0.08 to 0.28, Z = 1.11, p = 0.27). CONCLUSION: Chronic nitrate supplementation improves time-trial performance ranging from 5 to 30 min. The Society of Chinese Scholars on Exercise Physiology and Fitness 2022-10 2022-07-05 /pmc/articles/PMC9287610/ /pubmed/35892115 http://dx.doi.org/10.1016/j.jesf.2022.06.004 Text en © 2022 The Society of Chinese Scholars on Exercise Physiology and Fitness. Published by Elsevier (Singapore) Pte Ltd. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Review Article
Wong, Tak Hiong
Sim, Alexiaa
Burns, Stephen F.
The effects of nitrate ingestion on high-intensity endurance time-trial performance: A systematic review and meta-analysis
title The effects of nitrate ingestion on high-intensity endurance time-trial performance: A systematic review and meta-analysis
title_full The effects of nitrate ingestion on high-intensity endurance time-trial performance: A systematic review and meta-analysis
title_fullStr The effects of nitrate ingestion on high-intensity endurance time-trial performance: A systematic review and meta-analysis
title_full_unstemmed The effects of nitrate ingestion on high-intensity endurance time-trial performance: A systematic review and meta-analysis
title_short The effects of nitrate ingestion on high-intensity endurance time-trial performance: A systematic review and meta-analysis
title_sort effects of nitrate ingestion on high-intensity endurance time-trial performance: a systematic review and meta-analysis
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9287610/
https://www.ncbi.nlm.nih.gov/pubmed/35892115
http://dx.doi.org/10.1016/j.jesf.2022.06.004
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