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Dynamics of tumor-associated macrophages in a quantitative systems pharmacology model of immunotherapy in triple-negative breast cancer
Quantitative systems pharmacology (QSP) modeling is an emerging mechanistic computational approach that couples drug pharmacokinetics/pharmacodynamics and the course of disease progression. It has begun to play important roles in drug development for complex diseases such as cancer, including triple...
Autores principales: | Wang, Hanwen, Zhao, Chen, Santa-Maria, Cesar A., Emens, Leisha A., Popel, Aleksander S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9287616/ https://www.ncbi.nlm.nih.gov/pubmed/35856032 http://dx.doi.org/10.1016/j.isci.2022.104702 |
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