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Dynamics of tumor-associated macrophages in a quantitative systems pharmacology model of immunotherapy in triple-negative breast cancer

Quantitative systems pharmacology (QSP) modeling is an emerging mechanistic computational approach that couples drug pharmacokinetics/pharmacodynamics and the course of disease progression. It has begun to play important roles in drug development for complex diseases such as cancer, including triple...

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Detalles Bibliográficos
Autores principales: Wang, Hanwen, Zhao, Chen, Santa-Maria, Cesar A., Emens, Leisha A., Popel, Aleksander S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9287616/
https://www.ncbi.nlm.nih.gov/pubmed/35856032
http://dx.doi.org/10.1016/j.isci.2022.104702

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