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3D-speckle-tracking echocardiography correlates with cardiovascular magnetic resonance imaging diagnosis of acute myocarditis – An observational study

BACKGROUND: The diagnostic importance of three-dimensional (3D) speckle-tracking strain-imaging echocardiography in patients with acute myocarditis remains unclear. The aim of this study was to test the diagnostic performance of 3D-speckle-tracking echocardiography compared to CMR (cardiovascular ma...

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Autores principales: Goody, Philip Roger, Zimmer, Sebastian, Öztürk, Can, Zimmer, Angela, Kreuz, Jens, Becher, Marc Ulrich, Isaak, Alexander, Luetkens, Julian, Sugiura, Atsushi, Jansen, Felix, Nickenig, Georg, Hammerstingl, Christoph, Tiyerili, Vedat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9287637/
https://www.ncbi.nlm.nih.gov/pubmed/35855974
http://dx.doi.org/10.1016/j.ijcha.2022.101081
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author Goody, Philip Roger
Zimmer, Sebastian
Öztürk, Can
Zimmer, Angela
Kreuz, Jens
Becher, Marc Ulrich
Isaak, Alexander
Luetkens, Julian
Sugiura, Atsushi
Jansen, Felix
Nickenig, Georg
Hammerstingl, Christoph
Tiyerili, Vedat
author_facet Goody, Philip Roger
Zimmer, Sebastian
Öztürk, Can
Zimmer, Angela
Kreuz, Jens
Becher, Marc Ulrich
Isaak, Alexander
Luetkens, Julian
Sugiura, Atsushi
Jansen, Felix
Nickenig, Georg
Hammerstingl, Christoph
Tiyerili, Vedat
author_sort Goody, Philip Roger
collection PubMed
description BACKGROUND: The diagnostic importance of three-dimensional (3D) speckle-tracking strain-imaging echocardiography in patients with acute myocarditis remains unclear. The aim of this study was to test the diagnostic performance of 3D-speckle-tracking echocardiography compared to CMR (cardiovascular magnetic resonance imaging) for the diagnosis of acute myocarditis. METHODS AND RESULTS: 45 patients with clinically suspected myocarditis were enrolled in our study (29% female, mean age: 43.9 ± 16.3 years, peak troponin I level: 1.38 ± 3.51 ng/ml). 3D full-volume echocardiographic images were obtained and offline 2D as well as 3D speckle-tracking analysis of regional and global LV deformation was performed. All patients received CMR scans and myocarditis was diagnosed in 29 subjects based on original Lake-Louise criteria. The 16 patients, in whom myocarditis was excluded by CMR, served as controls. Regional changes in myocardial texture (diagnosed by CMR) were significantly associated with regional impairment of circumferential, longitudinal, and radial strain, as well as regional 3D displacement and total 3D strain. Interestingly, the 2D and 3D global longitudinal strain (GLS) showed higher diagnostic performance than well-known parameters associated with myocarditis, such as LVEF (as obtained by echocardiography and CMR) and LVEDV (as obtained by CMR). CONCLUSIONS: In this study, we examined the use of 3D-speckle-tracking echocardiography in patients with acute myocarditis. Global longitudinal strain was significantly impaired in patients with acute myocarditis and correlated with CMR findings. Therefore, 3D echocardiography could become a useful diagnostic tool in the primary diagnosis of myocarditis.
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spelling pubmed-92876372022-07-17 3D-speckle-tracking echocardiography correlates with cardiovascular magnetic resonance imaging diagnosis of acute myocarditis – An observational study Goody, Philip Roger Zimmer, Sebastian Öztürk, Can Zimmer, Angela Kreuz, Jens Becher, Marc Ulrich Isaak, Alexander Luetkens, Julian Sugiura, Atsushi Jansen, Felix Nickenig, Georg Hammerstingl, Christoph Tiyerili, Vedat Int J Cardiol Heart Vasc Original Paper BACKGROUND: The diagnostic importance of three-dimensional (3D) speckle-tracking strain-imaging echocardiography in patients with acute myocarditis remains unclear. The aim of this study was to test the diagnostic performance of 3D-speckle-tracking echocardiography compared to CMR (cardiovascular magnetic resonance imaging) for the diagnosis of acute myocarditis. METHODS AND RESULTS: 45 patients with clinically suspected myocarditis were enrolled in our study (29% female, mean age: 43.9 ± 16.3 years, peak troponin I level: 1.38 ± 3.51 ng/ml). 3D full-volume echocardiographic images were obtained and offline 2D as well as 3D speckle-tracking analysis of regional and global LV deformation was performed. All patients received CMR scans and myocarditis was diagnosed in 29 subjects based on original Lake-Louise criteria. The 16 patients, in whom myocarditis was excluded by CMR, served as controls. Regional changes in myocardial texture (diagnosed by CMR) were significantly associated with regional impairment of circumferential, longitudinal, and radial strain, as well as regional 3D displacement and total 3D strain. Interestingly, the 2D and 3D global longitudinal strain (GLS) showed higher diagnostic performance than well-known parameters associated with myocarditis, such as LVEF (as obtained by echocardiography and CMR) and LVEDV (as obtained by CMR). CONCLUSIONS: In this study, we examined the use of 3D-speckle-tracking echocardiography in patients with acute myocarditis. Global longitudinal strain was significantly impaired in patients with acute myocarditis and correlated with CMR findings. Therefore, 3D echocardiography could become a useful diagnostic tool in the primary diagnosis of myocarditis. Elsevier 2022-07-12 /pmc/articles/PMC9287637/ /pubmed/35855974 http://dx.doi.org/10.1016/j.ijcha.2022.101081 Text en © 2022 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Original Paper
Goody, Philip Roger
Zimmer, Sebastian
Öztürk, Can
Zimmer, Angela
Kreuz, Jens
Becher, Marc Ulrich
Isaak, Alexander
Luetkens, Julian
Sugiura, Atsushi
Jansen, Felix
Nickenig, Georg
Hammerstingl, Christoph
Tiyerili, Vedat
3D-speckle-tracking echocardiography correlates with cardiovascular magnetic resonance imaging diagnosis of acute myocarditis – An observational study
title 3D-speckle-tracking echocardiography correlates with cardiovascular magnetic resonance imaging diagnosis of acute myocarditis – An observational study
title_full 3D-speckle-tracking echocardiography correlates with cardiovascular magnetic resonance imaging diagnosis of acute myocarditis – An observational study
title_fullStr 3D-speckle-tracking echocardiography correlates with cardiovascular magnetic resonance imaging diagnosis of acute myocarditis – An observational study
title_full_unstemmed 3D-speckle-tracking echocardiography correlates with cardiovascular magnetic resonance imaging diagnosis of acute myocarditis – An observational study
title_short 3D-speckle-tracking echocardiography correlates with cardiovascular magnetic resonance imaging diagnosis of acute myocarditis – An observational study
title_sort 3d-speckle-tracking echocardiography correlates with cardiovascular magnetic resonance imaging diagnosis of acute myocarditis – an observational study
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9287637/
https://www.ncbi.nlm.nih.gov/pubmed/35855974
http://dx.doi.org/10.1016/j.ijcha.2022.101081
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