Astrocytes modulate neurodegenerative phenotypes associated with glaucoma in OPTN(E50K) human stem cell-derived retinal ganglion cells

Although the degeneration of retinal ganglion cells (RGCs) is a primary characteristic of glaucoma, astrocytes also contribute to their neurodegeneration in disease states. Although studies often explore cell-autonomous aspects of RGC neurodegeneration, a more comprehensive model of glaucoma should...

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Detalles Bibliográficos
Autores principales: Gomes, Cátia, VanderWall, Kirstin B., Pan, Yanling, Lu, Xiaoyu, Lavekar, Sailee S., Huang, Kang-Chieh, Fligor, Clarisse M., Harkin, Jade, Zhang, Chi, Cummins, Theodore R., Meyer, Jason S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9287669/
https://www.ncbi.nlm.nih.gov/pubmed/35714595
http://dx.doi.org/10.1016/j.stemcr.2022.05.006

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