The role of CDK8 in mesenchymal stem cells in controlling osteoclastogenesis and bone homeostasis

Bone marrow mesenchymal stem cells (MSCs) are critical regulators of postnatal bone homeostasis. Osteoporosis is characterized by bone volume and strength deterioration, partly due to MSC dysfunction. Cyclin-dependent kinase 8 (CDK8) belongs to the transcription-related CDK family. Here, CDK8 in MSC...

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Detalles Bibliográficos
Autores principales: Yamada, Takanori, Fukasawa, Kazuya, Horie, Tetsuhiro, Kadota, Takuya, Lyu, Jiajun, Tokumura, Kazuya, Ochiai, Shinsuke, Iwahashi, Sayuki, Suzuki, Akane, Park, Gyujin, Ueda, Rie, Yamamoto, Megumi, Kitao, Tatsuya, Shirahase, Hiroaki, Ochi, Hiroki, Sato, Shingo, Iezaki, Takashi, Hinoi, Eiichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9287674/
https://www.ncbi.nlm.nih.gov/pubmed/35777359
http://dx.doi.org/10.1016/j.stemcr.2022.06.001

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