Upregulation of β-catenin due to loss of miR-139 contributes to motor neuron death in amyotrophic lateral sclerosis

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by the loss of motor neurons (MNs). There are no effective treatments and patients usually die within 2–5 years of diagnosis. Emerging commonalities between familial and sporadic cases of this complex multifactori...

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Detalles Bibliográficos
Autores principales: Hawkins, Sophie, Namboori, Seema C., Tariq, Ammarah, Blaker, Catherine, Flaxman, Christine, Dey, Nidhi S., Henley, Peter, Randall, Andrew, Rosa, Alessandro, Stanton, Lawrence W., Bhinge, Akshay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9287677/
https://www.ncbi.nlm.nih.gov/pubmed/35750046
http://dx.doi.org/10.1016/j.stemcr.2022.05.019

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