Transient DUX4 expression in human embryonic stem cells induces blastomere-like expression program that is marked by SLC34A2

Embryonic genome activation (EGA) is critical for embryonic development. However, our understanding of the regulatory mechanisms of human EGA is still incomplete. Human embryonic stem cells (hESCs) are an established model for studying developmental processes, but they resemble epiblast and are sub-...

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Detalles Bibliográficos
Autores principales: Yoshihara, Masahito, Kirjanov, Ida, Nykänen, Sonja, Sokka, Joonas, Weltner, Jere, Lundin, Karolina, Gawriyski, Lisa, Jouhilahti, Eeva-Mari, Varjosalo, Markku, Tervaniemi, Mari H., Otonkoski, Timo, Trokovic, Ras, Katayama, Shintaro, Vuoristo, Sanna, Kere, Juha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9287684/
https://www.ncbi.nlm.nih.gov/pubmed/35777358
http://dx.doi.org/10.1016/j.stemcr.2022.06.002

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