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Recent advances in “sickle and niche” research - Tribute to Dr. Paul S Frenette -

In this retrospective, we review the two research topics that formed the basis of the outstanding career of Dr. Paul S. Frenette. In the first part, we focus on sickle cell disease (SCD). The defining feature of SCD is polymerization of the deoxygenated mutant hemoglobin, which leads to a vicious cy...

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Detalles Bibliográficos
Autores principales: Torres, Lidiane S., Asada, Noboru, Weiss, Mitchell J., Trumpp, Andreas, Suda, Toshio, Scadden, David T., Ito, Keisuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9287685/
https://www.ncbi.nlm.nih.gov/pubmed/35830837
http://dx.doi.org/10.1016/j.stemcr.2022.06.004