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Adiponectin/AdiopR1 signaling prevents mitochondrial dysfunction and oxidative injury after traumatic brain injury in a SIRT3 dependent manner
Mitochondrial dysfunction and oxidative injury, which contribute to worsening of neurological deficits and poor clinical outcomes, are hallmarks of secondary brain injury after TBI. Adiponectin (APN), beyond its well-established regulatory effects on metabolism, is also essential for maintaining nor...
Autores principales: | Zhang, Shenghao, Wu, Xun, Wang, Jin, Shi, Yingwu, Hu, Qing, Cui, Wenxing, Bai, Hao, Zhou, Jinpeng, Du, Yong, Han, Liying, Li, Leiyang, Feng, Dayun, Ge, Shunnan, Qu, Yan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9287731/ https://www.ncbi.nlm.nih.gov/pubmed/35793583 http://dx.doi.org/10.1016/j.redox.2022.102390 |
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