Transketolase in human Müller cells is critical to resist light stress through the pentose phosphate and NRF2 pathways

The Pentose Phosphate Pathway (PPP), a metabolic offshoot of the glycolytic pathway, provides protective metabolites and molecules essential for cell redox balance and survival. Transketolase (TKT) is the critical enzyme that controls the extent of “traffic flow” through the PPP. Here, we explored t...

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Detalles Bibliográficos
Autores principales: Chen, Yingying, Zhang, Ting, Zeng, Shaoxue, Xu, Rong, Jin, Kaiyu, Coorey, Nathan J., Wang, Yekai, Wang, Ke, Lee, So-Ra, Yam, Michelle, Zhu, Meidong, Chang, Andrew, Fan, Xiaohui, Zhang, Meixia, Du, Jianhai, Gillies, Mark C., Zhu, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9287732/
https://www.ncbi.nlm.nih.gov/pubmed/35779441
http://dx.doi.org/10.1016/j.redox.2022.102379

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