Cargando…
Motor training is improved by concurrent application of slow oscillating transcranial alternating current stimulation to motor cortex
Physical exercise and neurorehabilitation involve repetitive training that can induce changes in motor performance arising from neuroplasticity. Retention of these motor changes occurs via an encoding process, during which rapid neuroplastic changes occur in response to training. Previous studies sh...
Autores principales: | , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9287859/ https://www.ncbi.nlm.nih.gov/pubmed/35840886 http://dx.doi.org/10.1186/s12868-022-00731-x |
_version_ | 1784748340963966976 |
---|---|
author | Sale, Martin V. Kuzovina, Anastasiia |
author_facet | Sale, Martin V. Kuzovina, Anastasiia |
author_sort | Sale, Martin V. |
collection | PubMed |
description | Physical exercise and neurorehabilitation involve repetitive training that can induce changes in motor performance arising from neuroplasticity. Retention of these motor changes occurs via an encoding process, during which rapid neuroplastic changes occur in response to training. Previous studies show that transcranial alternating current stimulation (tACS), a form of non-invasive brain stimulation, can enhance encoding of a cognitive learning task during wakefulness. However, the effect of tACS on motor processes in the awake brain is unknown. In this study, forty-two healthy 18–35 year old participants received either 0.75 Hz (active) tACS (or sham stimulation) for 30 min during a ballistic thumb abduction motor training task. Training-related behavioural effects were quantified by assessing changes in thumb abduction acceleration, and neuroplastic changes were quantified by measuring motor evoked potential (MEP) amplitude of the abductor pollicis brevis muscle. These measures were reassessed immediately after the motor training task to quantify short-term changes, and then 24 h later to assess longer-term changes. Thumb abduction acceleration in both active and sham stimulation conditions increased immediately after the motor learning, consistent with effective training. Critically, participants in the active group maintained significantly higher thumb acceleration 24 h later (t(40) = 2.810, P = 0.044). There were no significant changes or inter-group differences in MEPs for both conditions. The results suggest that 0.75 Hz tACS applied during motor training enhances the effectiveness of motor training, which manifests as enhancement in longer-term task benefits. |
format | Online Article Text |
id | pubmed-9287859 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-92878592022-07-17 Motor training is improved by concurrent application of slow oscillating transcranial alternating current stimulation to motor cortex Sale, Martin V. Kuzovina, Anastasiia BMC Neurosci Research Physical exercise and neurorehabilitation involve repetitive training that can induce changes in motor performance arising from neuroplasticity. Retention of these motor changes occurs via an encoding process, during which rapid neuroplastic changes occur in response to training. Previous studies show that transcranial alternating current stimulation (tACS), a form of non-invasive brain stimulation, can enhance encoding of a cognitive learning task during wakefulness. However, the effect of tACS on motor processes in the awake brain is unknown. In this study, forty-two healthy 18–35 year old participants received either 0.75 Hz (active) tACS (or sham stimulation) for 30 min during a ballistic thumb abduction motor training task. Training-related behavioural effects were quantified by assessing changes in thumb abduction acceleration, and neuroplastic changes were quantified by measuring motor evoked potential (MEP) amplitude of the abductor pollicis brevis muscle. These measures were reassessed immediately after the motor training task to quantify short-term changes, and then 24 h later to assess longer-term changes. Thumb abduction acceleration in both active and sham stimulation conditions increased immediately after the motor learning, consistent with effective training. Critically, participants in the active group maintained significantly higher thumb acceleration 24 h later (t(40) = 2.810, P = 0.044). There were no significant changes or inter-group differences in MEPs for both conditions. The results suggest that 0.75 Hz tACS applied during motor training enhances the effectiveness of motor training, which manifests as enhancement in longer-term task benefits. BioMed Central 2022-07-15 /pmc/articles/PMC9287859/ /pubmed/35840886 http://dx.doi.org/10.1186/s12868-022-00731-x Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Research Sale, Martin V. Kuzovina, Anastasiia Motor training is improved by concurrent application of slow oscillating transcranial alternating current stimulation to motor cortex |
title | Motor training is improved by concurrent application of slow oscillating transcranial alternating current stimulation to motor cortex |
title_full | Motor training is improved by concurrent application of slow oscillating transcranial alternating current stimulation to motor cortex |
title_fullStr | Motor training is improved by concurrent application of slow oscillating transcranial alternating current stimulation to motor cortex |
title_full_unstemmed | Motor training is improved by concurrent application of slow oscillating transcranial alternating current stimulation to motor cortex |
title_short | Motor training is improved by concurrent application of slow oscillating transcranial alternating current stimulation to motor cortex |
title_sort | motor training is improved by concurrent application of slow oscillating transcranial alternating current stimulation to motor cortex |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9287859/ https://www.ncbi.nlm.nih.gov/pubmed/35840886 http://dx.doi.org/10.1186/s12868-022-00731-x |
work_keys_str_mv | AT salemartinv motortrainingisimprovedbyconcurrentapplicationofslowoscillatingtranscranialalternatingcurrentstimulationtomotorcortex AT kuzovinaanastasiia motortrainingisimprovedbyconcurrentapplicationofslowoscillatingtranscranialalternatingcurrentstimulationtomotorcortex |