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Ozone induces autophagy by activating PPARγ/mTOR in rat chondrocytes treated with IL-1β

BACKGROUND: Osteoarthritis (OA) is the main cause of older pain and disability. Intra-articular injections of ozone (O(3)) commonly have been found to have antioxidative and anti-inflammatory effects to reduce pain and improve function in knee osteoarthritis. It has been reported that reduced autoph...

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Detalles Bibliográficos
Autores principales: Sun, Panpan, Xu, Weicheng, Zhao, Xu, Zhang, Cong, Lin, Xiaowen, Gong, Moxuan, Fu, Zhijian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9287877/
https://www.ncbi.nlm.nih.gov/pubmed/35842709
http://dx.doi.org/10.1186/s13018-022-03233-y