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Super-enhancer profiling identifies novel critical and targetable cancer survival gene LYL1 in pediatric acute myeloid leukemia

BACKGROUND: Acute myeloid leukemia (AML) is a myeloid neoplasm makes up 7.6% of hematopoietic malignancies. Super-enhancers (SEs) represent a special group of enhancers, which have been reported in multiple cell types. In this study, we explored super-enhancer profiling through ChIP-Seq analysis of...

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Detalles Bibliográficos
Autores principales:	Fang, Fang, Lu, Jun, Sang, Xu, Tao, Yan-Fang, Wang, Jian-Wei, Zhang, Zi-Mu, Zhang, Yong-Ping, Li, Xiao-Lu, Xie, Yi, Wu, Shui-Yan, Chu, Xin-Ran, Li, Gen, Wu, Di, Chen, Yan-Ling, Yu, Juan-Juan, Jia, Si-qi, Feng, Chen-xi, Tian, Yuan-Yuan, Li, Zhi-Heng, Ling, Jing, Hu, Shao-Yan, Pan, Jian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9288051/ https://www.ncbi.nlm.nih.gov/pubmed/35842703 http://dx.doi.org/10.1186/s13046-022-02428-9

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