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Efficacy of 3% hydrogen peroxide solution in cleaning tongue coating before and after surgery: a randomized phase II study

BACKGROUND: Increased bacterial presence in the tongue coating and thereby, the saliva, may be a risk factor for postoperative complications such as surgical site infection or postoperative pneumonia after cancer surgery. However, no method for cleaning tongue coating has been established experiment...

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Autores principales: Soutome, Sakiko, Otsuru, Mitsunobu, Hayashida, Saki, Naruse, Tomofumi, Morishita, Kota, Kurihara, Kazumi, Kawashita, Yumiko, Funahara, Madoka, Umeda, Masahiro, Taniguchi, Hideki, Saito, Toshiyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9288054/
https://www.ncbi.nlm.nih.gov/pubmed/35841016
http://dx.doi.org/10.1186/s12903-022-02325-9
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author Soutome, Sakiko
Otsuru, Mitsunobu
Hayashida, Saki
Naruse, Tomofumi
Morishita, Kota
Kurihara, Kazumi
Kawashita, Yumiko
Funahara, Madoka
Umeda, Masahiro
Taniguchi, Hideki
Saito, Toshiyuki
author_facet Soutome, Sakiko
Otsuru, Mitsunobu
Hayashida, Saki
Naruse, Tomofumi
Morishita, Kota
Kurihara, Kazumi
Kawashita, Yumiko
Funahara, Madoka
Umeda, Masahiro
Taniguchi, Hideki
Saito, Toshiyuki
author_sort Soutome, Sakiko
collection PubMed
description BACKGROUND: Increased bacterial presence in the tongue coating and thereby, the saliva, may be a risk factor for postoperative complications such as surgical site infection or postoperative pneumonia after cancer surgery. However, no method for cleaning tongue coating has been established experimentally. The purpose of this study was to verify the effect of brushing with 3% hydrogen peroxide on suppression of the number of bacteria in tongue coating. METHODS: Sixteen patients with gastric cancer or colorectal cancer undergoing surgery were randomly allocated to control and intervention groups. In the control group, the tongue was brushed for 30 s with a water-moistened toothbrush, while in the intervention group, the tongue was brushed for 30 s with a toothbrush moistened with 3% hydrogen peroxide. Bacterial counts on tongue coating were measured before and 30 s after cleaning the tongue coating using the Rapid Oral Bacteria Quantification System. RESULTS: In the control group, the number of bacteria on the tongue did not decrease significantly after tongue cleaning on the day before surgery, but did on the day after surgery. In contrast, in the intervention group, the number of bacteria on the tongue decreased significantly after tongue cleaning both on the day before and the day after surgery. Furthermore, when comparing the control and intervention groups, the intervention group had a greater reduction effect. CONCLUSIONS: Tongue brushing with 3% hydrogen peroxide is a useful method to reduce the number of bacteria on the tongue in patients with gastrointestinal cancer undergoing surgery. Trial registration jRCTs071200020 (July 3, 2020).
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spelling pubmed-92880542022-07-17 Efficacy of 3% hydrogen peroxide solution in cleaning tongue coating before and after surgery: a randomized phase II study Soutome, Sakiko Otsuru, Mitsunobu Hayashida, Saki Naruse, Tomofumi Morishita, Kota Kurihara, Kazumi Kawashita, Yumiko Funahara, Madoka Umeda, Masahiro Taniguchi, Hideki Saito, Toshiyuki BMC Oral Health Research BACKGROUND: Increased bacterial presence in the tongue coating and thereby, the saliva, may be a risk factor for postoperative complications such as surgical site infection or postoperative pneumonia after cancer surgery. However, no method for cleaning tongue coating has been established experimentally. The purpose of this study was to verify the effect of brushing with 3% hydrogen peroxide on suppression of the number of bacteria in tongue coating. METHODS: Sixteen patients with gastric cancer or colorectal cancer undergoing surgery were randomly allocated to control and intervention groups. In the control group, the tongue was brushed for 30 s with a water-moistened toothbrush, while in the intervention group, the tongue was brushed for 30 s with a toothbrush moistened with 3% hydrogen peroxide. Bacterial counts on tongue coating were measured before and 30 s after cleaning the tongue coating using the Rapid Oral Bacteria Quantification System. RESULTS: In the control group, the number of bacteria on the tongue did not decrease significantly after tongue cleaning on the day before surgery, but did on the day after surgery. In contrast, in the intervention group, the number of bacteria on the tongue decreased significantly after tongue cleaning both on the day before and the day after surgery. Furthermore, when comparing the control and intervention groups, the intervention group had a greater reduction effect. CONCLUSIONS: Tongue brushing with 3% hydrogen peroxide is a useful method to reduce the number of bacteria on the tongue in patients with gastrointestinal cancer undergoing surgery. Trial registration jRCTs071200020 (July 3, 2020). BioMed Central 2022-07-15 /pmc/articles/PMC9288054/ /pubmed/35841016 http://dx.doi.org/10.1186/s12903-022-02325-9 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Soutome, Sakiko
Otsuru, Mitsunobu
Hayashida, Saki
Naruse, Tomofumi
Morishita, Kota
Kurihara, Kazumi
Kawashita, Yumiko
Funahara, Madoka
Umeda, Masahiro
Taniguchi, Hideki
Saito, Toshiyuki
Efficacy of 3% hydrogen peroxide solution in cleaning tongue coating before and after surgery: a randomized phase II study
title Efficacy of 3% hydrogen peroxide solution in cleaning tongue coating before and after surgery: a randomized phase II study
title_full Efficacy of 3% hydrogen peroxide solution in cleaning tongue coating before and after surgery: a randomized phase II study
title_fullStr Efficacy of 3% hydrogen peroxide solution in cleaning tongue coating before and after surgery: a randomized phase II study
title_full_unstemmed Efficacy of 3% hydrogen peroxide solution in cleaning tongue coating before and after surgery: a randomized phase II study
title_short Efficacy of 3% hydrogen peroxide solution in cleaning tongue coating before and after surgery: a randomized phase II study
title_sort efficacy of 3% hydrogen peroxide solution in cleaning tongue coating before and after surgery: a randomized phase ii study
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9288054/
https://www.ncbi.nlm.nih.gov/pubmed/35841016
http://dx.doi.org/10.1186/s12903-022-02325-9
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