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The DDR-related gene signature with cell cycle checkpoint function predicts prognosis, immune activity, and chemoradiotherapy response in lung adenocarcinoma

BACKGROUND: As a DNA surveillance mechanism, cell cycle checkpoint has recently been discovered to be closely associated with lung adenocarcinoma (LUAD) prognosis. It is also an essential link in the process of DNA damage repair (DDR) that confers resistance to radiotherapy. Whether genes that have...

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Detalles Bibliográficos
Autores principales: Li, Quan, Zhang, Pan, Hu, Huixiao, Huang, Hang, Pan, Dong, Mao, Guangyun, Hu, Burong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9288070/
https://www.ncbi.nlm.nih.gov/pubmed/35840978
http://dx.doi.org/10.1186/s12931-022-02110-w