Inhibition of AMPK/PFKFB3 mediated glycolysis synergizes with penfluridol to suppress gallbladder cancer growth

BACKGROUND: Penfluridol (PF) is an FDA-approved antipsychotic drug that has recently been shown to have anticancer activity. However, the anticancer effects and underlying mechanisms of PF are not well-established in gallbladder cancer (GBC). METHODS: The anticancer efficacy of PF on GBC was investi...

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Detalles Bibliográficos
Autores principales: Hu, Jiahao, Cao, Jiasheng, Jin, Ren’an, Zhang, Bin, Topatana, Win, Juengpanich, Sarun, Li, Shijie, Chen, Tian’en, Lu, Ziyi, Cai, Xiujun, Chen, Mingyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9288071/
https://www.ncbi.nlm.nih.gov/pubmed/35842652
http://dx.doi.org/10.1186/s12964-022-00882-8

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