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Efficacy of an Anti-Semaphorin 3A Neutralizing Antibody in a Male Experimental Retinal Vein Occlusion Mouse Model

PURPOSE: Semaphorin 3A (Sema3A) is a promising therapeutic target for macular edema in age-related macular degeneration, diabetic retinopathy, and retinal vein occlusion (RVO). Anti-vascular endothelial growth factors (anti-VEGFs) are the current standard of care for many retinal diseases. This stud...

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Detalles Bibliográficos
Autores principales: Nakamura, Shinsuke, Nishinaka, Anri, Hidaka, Yae, Shimazawa, Masamitsu, Thomas, Leo, Bakker, Remko A., Hara, Hideaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9288153/
https://www.ncbi.nlm.nih.gov/pubmed/35822950
http://dx.doi.org/10.1167/iovs.63.8.14