The Effect of Heparin and Its Preparations on Disseminated Intravascular Coagulation Mortality and Hospitalization: A Systematic Review

METHODS: The databases of PubMed, Scopus, Embase, and Web of Science were searched systematically up to November 2021. The quality of RCTs was assessed by Cochrane Collaboration's tool and the risk of bias was assessed for cohort studies through NOS score. RESULTS: Out of 3288 articles, eight s...

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Autores principales: Omidkhoda, Navid, Abedi, Farshad, Ghavami, Vahid, Rahimi, Hossein, Samadi, Sara, Arasteh, Omid, Mohammadpour, Amir Hooshang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9288321/
https://www.ncbi.nlm.nih.gov/pubmed/35855054
http://dx.doi.org/10.1155/2022/2226761
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author Omidkhoda, Navid
Abedi, Farshad
Ghavami, Vahid
Rahimi, Hossein
Samadi, Sara
Arasteh, Omid
Mohammadpour, Amir Hooshang
author_facet Omidkhoda, Navid
Abedi, Farshad
Ghavami, Vahid
Rahimi, Hossein
Samadi, Sara
Arasteh, Omid
Mohammadpour, Amir Hooshang
author_sort Omidkhoda, Navid
collection PubMed
description METHODS: The databases of PubMed, Scopus, Embase, and Web of Science were searched systematically up to November 2021. The quality of RCTs was assessed by Cochrane Collaboration's tool and the risk of bias was assessed for cohort studies through NOS score. RESULTS: Out of 3288 articles, eight studies were eligible to be included in this study. Our review retrieved six RCTs and two retrospective cohort studies consisting of 950 participants diagnosed by DIC. A significant effect of heparin on DIC mortality was identified in four studies. Furthermore, heparin was used as a control group in three studies. CONCLUSIONS: We concluded that administration of heparin and its preparations in DIC patients could reduce the mortality rate and duration of hospitalization, especially in the earlier stages of DIC.
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spelling pubmed-92883212022-07-18 The Effect of Heparin and Its Preparations on Disseminated Intravascular Coagulation Mortality and Hospitalization: A Systematic Review Omidkhoda, Navid Abedi, Farshad Ghavami, Vahid Rahimi, Hossein Samadi, Sara Arasteh, Omid Mohammadpour, Amir Hooshang Int J Clin Pract Review Article METHODS: The databases of PubMed, Scopus, Embase, and Web of Science were searched systematically up to November 2021. The quality of RCTs was assessed by Cochrane Collaboration's tool and the risk of bias was assessed for cohort studies through NOS score. RESULTS: Out of 3288 articles, eight studies were eligible to be included in this study. Our review retrieved six RCTs and two retrospective cohort studies consisting of 950 participants diagnosed by DIC. A significant effect of heparin on DIC mortality was identified in four studies. Furthermore, heparin was used as a control group in three studies. CONCLUSIONS: We concluded that administration of heparin and its preparations in DIC patients could reduce the mortality rate and duration of hospitalization, especially in the earlier stages of DIC. Hindawi 2022-07-09 /pmc/articles/PMC9288321/ /pubmed/35855054 http://dx.doi.org/10.1155/2022/2226761 Text en Copyright © 2022 Navid Omidkhoda et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Omidkhoda, Navid
Abedi, Farshad
Ghavami, Vahid
Rahimi, Hossein
Samadi, Sara
Arasteh, Omid
Mohammadpour, Amir Hooshang
The Effect of Heparin and Its Preparations on Disseminated Intravascular Coagulation Mortality and Hospitalization: A Systematic Review
title The Effect of Heparin and Its Preparations on Disseminated Intravascular Coagulation Mortality and Hospitalization: A Systematic Review
title_full The Effect of Heparin and Its Preparations on Disseminated Intravascular Coagulation Mortality and Hospitalization: A Systematic Review
title_fullStr The Effect of Heparin and Its Preparations on Disseminated Intravascular Coagulation Mortality and Hospitalization: A Systematic Review
title_full_unstemmed The Effect of Heparin and Its Preparations on Disseminated Intravascular Coagulation Mortality and Hospitalization: A Systematic Review
title_short The Effect of Heparin and Its Preparations on Disseminated Intravascular Coagulation Mortality and Hospitalization: A Systematic Review
title_sort effect of heparin and its preparations on disseminated intravascular coagulation mortality and hospitalization: a systematic review
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9288321/
https://www.ncbi.nlm.nih.gov/pubmed/35855054
http://dx.doi.org/10.1155/2022/2226761
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