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The radiosensitizing effect of β-Thujaplicin, a tropolone derivative inducing S-phase cell cycle arrest, in head and neck squamous cell carcinoma-derived cell lines
BACKGROUND: Resistance to radiotherapy is a common cause of treatment failure in advanced head and neck squamous cell carcinoma (HNSCC). ß-Thujaplicin, a natural tropolone derivative, acts as an anti-cancer agent and has recently been shown to radiosensitize non-HNSCC cancer cells. However, no data...
Autores principales: | Haas, Markus, Lenz, Teresa, Kadletz-Wanke, Lorenz, Heiduschka, Gregor, Jank, Bernhard J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9288374/ https://www.ncbi.nlm.nih.gov/pubmed/35412173 http://dx.doi.org/10.1007/s10637-022-01229-3 |
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