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Ghrelin rapidly elevates protein synthesis in vitro by employing the rpS6K-eEF2K-eEF2 signalling axis

Activated ghrelin receptor GHS-R1α triggers cell signalling pathways that modulate energy homeostasis and biosynthetic processes. However, the effects of ghrelin on mRNA translation are unknown. Using various reporter assays, here we demonstrate a rapid elevation of protein synthesis in cells within...

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Detalles Bibliográficos
Autores principales:	Zhdanov, Alexander V., Golubeva, Anna V., Yordanova, Martina M., Andreev, Dmitry E., Ventura-Silva, Ana Paula, Schellekens, Harriet, Baranov, Pavel V., Cryan, John F., Papkovsky, Dmitri B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9288388/ https://www.ncbi.nlm.nih.gov/pubmed/35841486 http://dx.doi.org/10.1007/s00018-022-04446-4

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