Reduced dynamic loads due to hip dislocation induce acetabular cartilage degeneration by IL-6 and MMP3 via the STAT3/periostin/NF-κB axis

Developmental dysplasia of the hip (DDH) is characterized by anatomical abnormalities of the hip joint, ranging from mild acetabular dysplasia to hip subluxation and eventually dislocation. The mechanism underlying the cartilage degeneration of the hip joints exposed to reduced dynamic loads due to...

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Detalles Bibliográficos
Autores principales: Nakamura, Yutaka, Saitou, Mitsuru, Komura, Shingo, Matsumoto, Kazu, Ogawa, Hiroyasu, Miyagawa, Takaki, Saitou, Takashi, Imamura, Takeshi, Imai, Yuuki, Takayanagi, Hiroshi, Akiyama, Haruhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9288549/
https://www.ncbi.nlm.nih.gov/pubmed/35842459
http://dx.doi.org/10.1038/s41598-022-16585-6

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