Notch-activated mesenchymal stromal/stem cells enhance the protective effect against acetaminophen-induced acute liver injury by activating AMPK/SIRT1 pathway

BACKGROUND: Notch signaling plays important roles in regulating innate immunity. However, little is known about the role of Notch in mesenchymal stromal/stem cell (MSC)-mediated immunomodulation during liver inflammatory response. METHODS: Notch activation in human umbilical cord-derived MSCs was pe...

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Detalles Bibliográficos
Autores principales: Yu, Mengxue, Zhou, Min, Li, Jiahui, Zong, Ruobin, Yan, Yufei, Kong, Liangyi, Zhu, Qiang, Li, Changyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9288678/
https://www.ncbi.nlm.nih.gov/pubmed/35842731
http://dx.doi.org/10.1186/s13287-022-02999-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9288678/
https://www.ncbi.nlm.nih.gov/pubmed/35842731
http://dx.doi.org/10.1186/s13287-022-02999-6

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