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Notch-activated mesenchymal stromal/stem cells enhance the protective effect against acetaminophen-induced acute liver injury by activating AMPK/SIRT1 pathway

BACKGROUND: Notch signaling plays important roles in regulating innate immunity. However, little is known about the role of Notch in mesenchymal stromal/stem cell (MSC)-mediated immunomodulation during liver inflammatory response. METHODS: Notch activation in human umbilical cord-derived MSCs was pe...

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Detalles Bibliográficos
Autores principales:	Yu, Mengxue, Zhou, Min, Li, Jiahui, Zong, Ruobin, Yan, Yufei, Kong, Liangyi, Zhu, Qiang, Li, Changyong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9288678/ https://www.ncbi.nlm.nih.gov/pubmed/35842731 http://dx.doi.org/10.1186/s13287-022-02999-6

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