Extracellular vesicles derived from human umbilical cord mesenchymal stem cells alleviate osteoarthritis of the knee in mice model by interacting with METTL3 to reduce m6A of NLRP3 in macrophage

BACKGROUND: Osteoarthritis (OA) is a prevalent degenerative joint disease that not only significantly impairs the quality of life of middle-aged and elderly individuals but also imposes a significant financial burden on patients and society. Due to their significant biological properties, extracellu...

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Detalles Bibliográficos
Autores principales: Zhou, Hao, Shen, Xun, Yan, Chen, Xiong, Wu, Ma, Zemeng, Tan, Zhenggang, Wang, Jinwen, Li, Yao, Liu, Jiuxiang, Duan, Ao, Liu, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9288728/
https://www.ncbi.nlm.nih.gov/pubmed/35842714
http://dx.doi.org/10.1186/s13287-022-03005-9

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