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Comparing short‐term/long‐term outcomes of heart transplants that occur inside and outside of normal working hours
AIMS: Heart transplantation involves many factors such as donor selection, recipient management, multidisciplinary assessment, coordination with other organ teams, and transportation. Because of some unpredictable factors, heart transplantation can be conducted at any time of day. The purpose of thi...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9288785/ https://www.ncbi.nlm.nih.gov/pubmed/35460200 http://dx.doi.org/10.1002/ehf2.13947 |
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author | Nishida, Hidefumi Salerno, Christopher Onsager, David Song, Tae Nguyen, Ann Grinstein, Jonathan Chung, Bow Smith, Bryan Kalantari, Sara Sarswat, Nitasha Kim, Gene Pinney, Sean Jeevanandam, Valluvan Ota, Takeyoshi |
author_facet | Nishida, Hidefumi Salerno, Christopher Onsager, David Song, Tae Nguyen, Ann Grinstein, Jonathan Chung, Bow Smith, Bryan Kalantari, Sara Sarswat, Nitasha Kim, Gene Pinney, Sean Jeevanandam, Valluvan Ota, Takeyoshi |
author_sort | Nishida, Hidefumi |
collection | PubMed |
description | AIMS: Heart transplantation involves many factors such as donor selection, recipient management, multidisciplinary assessment, coordination with other organ teams, and transportation. Because of some unpredictable factors, heart transplantation can be conducted at any time of day. The purpose of this study is to investigate if outcomes differ between heart transplants taking place inside or outside of normal working hours. METHODS AND RESULTS: We reviewed patients who underwent heart transplantation at our institution from January 2010 to July 2020 (n = 329). Based on the documented start time of the recipient surgeries, the cohort was divided into two groups: working hours (Group A: 7:30 to 17:00; n = 92) and after hours (Group B: 17:00 to 7:30; n = 237). We compared these groups using propensity score matching analysis. After propensity score matching, 78 pairs of patients were successfully matched. We reviewed early and late clinical outcomes including survival. Long‐term survival was compared using the Kaplan–Meier method. In the propensity‐score matched patients, there were no significant differences in the baseline characteristics between two groups. In‐hospital mortality was not significantly different between the two groups (Group A: 6.4% vs. Group B: 2.6%, P = 0.44). Ischaemic time and cross‐clamp time did not differ between the groups. In terms of postoperative complications, there were no significant differences between two groups in stroke (6.4% vs. 3.9%, P = 0.72), primary graft dysfunction requiring extracorporeal membrane oxygenation (5.1% vs. 7.7%, P = 0.75), re‐exploration for bleeding (9.0% vs. 12.8%, P = 0.44), and newly required haemodialysis (7.7% vs. 6.4%, P = 0.75). The survival rate in Group A (88.1% at 1 year, 81.3% at 3 years) was not significantly different from Group B (90.5% at 1 year, 82.3% at 3 years, log rank = 0.96). CONCLUSION: There was no significant difference in clinical outcomes between heart transplants taking place inside or outside of working hours. A high quality of care can be provided for heart transplant patients even during after hours. |
format | Online Article Text |
id | pubmed-9288785 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-92887852022-07-19 Comparing short‐term/long‐term outcomes of heart transplants that occur inside and outside of normal working hours Nishida, Hidefumi Salerno, Christopher Onsager, David Song, Tae Nguyen, Ann Grinstein, Jonathan Chung, Bow Smith, Bryan Kalantari, Sara Sarswat, Nitasha Kim, Gene Pinney, Sean Jeevanandam, Valluvan Ota, Takeyoshi ESC Heart Fail Original Articles AIMS: Heart transplantation involves many factors such as donor selection, recipient management, multidisciplinary assessment, coordination with other organ teams, and transportation. Because of some unpredictable factors, heart transplantation can be conducted at any time of day. The purpose of this study is to investigate if outcomes differ between heart transplants taking place inside or outside of normal working hours. METHODS AND RESULTS: We reviewed patients who underwent heart transplantation at our institution from January 2010 to July 2020 (n = 329). Based on the documented start time of the recipient surgeries, the cohort was divided into two groups: working hours (Group A: 7:30 to 17:00; n = 92) and after hours (Group B: 17:00 to 7:30; n = 237). We compared these groups using propensity score matching analysis. After propensity score matching, 78 pairs of patients were successfully matched. We reviewed early and late clinical outcomes including survival. Long‐term survival was compared using the Kaplan–Meier method. In the propensity‐score matched patients, there were no significant differences in the baseline characteristics between two groups. In‐hospital mortality was not significantly different between the two groups (Group A: 6.4% vs. Group B: 2.6%, P = 0.44). Ischaemic time and cross‐clamp time did not differ between the groups. In terms of postoperative complications, there were no significant differences between two groups in stroke (6.4% vs. 3.9%, P = 0.72), primary graft dysfunction requiring extracorporeal membrane oxygenation (5.1% vs. 7.7%, P = 0.75), re‐exploration for bleeding (9.0% vs. 12.8%, P = 0.44), and newly required haemodialysis (7.7% vs. 6.4%, P = 0.75). The survival rate in Group A (88.1% at 1 year, 81.3% at 3 years) was not significantly different from Group B (90.5% at 1 year, 82.3% at 3 years, log rank = 0.96). CONCLUSION: There was no significant difference in clinical outcomes between heart transplants taking place inside or outside of working hours. A high quality of care can be provided for heart transplant patients even during after hours. John Wiley and Sons Inc. 2022-04-23 /pmc/articles/PMC9288785/ /pubmed/35460200 http://dx.doi.org/10.1002/ehf2.13947 Text en © 2022 The Authors. ESC Heart Failure published by John Wiley & Sons Ltd on behalf of European Society of Cardiology. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made. |
spellingShingle | Original Articles Nishida, Hidefumi Salerno, Christopher Onsager, David Song, Tae Nguyen, Ann Grinstein, Jonathan Chung, Bow Smith, Bryan Kalantari, Sara Sarswat, Nitasha Kim, Gene Pinney, Sean Jeevanandam, Valluvan Ota, Takeyoshi Comparing short‐term/long‐term outcomes of heart transplants that occur inside and outside of normal working hours |
title | Comparing short‐term/long‐term outcomes of heart transplants that occur inside and outside of normal working hours |
title_full | Comparing short‐term/long‐term outcomes of heart transplants that occur inside and outside of normal working hours |
title_fullStr | Comparing short‐term/long‐term outcomes of heart transplants that occur inside and outside of normal working hours |
title_full_unstemmed | Comparing short‐term/long‐term outcomes of heart transplants that occur inside and outside of normal working hours |
title_short | Comparing short‐term/long‐term outcomes of heart transplants that occur inside and outside of normal working hours |
title_sort | comparing short‐term/long‐term outcomes of heart transplants that occur inside and outside of normal working hours |
topic | Original Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9288785/ https://www.ncbi.nlm.nih.gov/pubmed/35460200 http://dx.doi.org/10.1002/ehf2.13947 |
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