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Epigenetic restoration and activation of ERβ: an inspiring approach for treatment of triple-negative breast cancer

BACKGROUND: Triple-negative breast cancer (TNBC) is one of the most aggressive subtypes of breast cancer. TNBC lacks targeted therapy receptors, rendering endocrine and HER2-targeted therapies ineffective. TNBC is typically treated with cytotoxic chemotherapy followed by surgery. Targeting epigeneti...

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Detalles Bibliográficos
Autores principales: Salahuddin, Ahmad, Ghanem, Heba, Omran, Gamal A., Helmy, Maged Wasfy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9288957/
https://www.ncbi.nlm.nih.gov/pubmed/35843988
http://dx.doi.org/10.1007/s12032-022-01765-1

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