Cargando…

Distinct type I interferon responses between younger women and older men contribute to the variability of COVID-19 outcomes: Hypothesis generating insights from COVID-19 convalescent individuals

BACKGROUND/OBJECTIVE: Older age and male sex have been consistently found to be associated with dismal outcomes among COVID-19 infected patients. In contrast, premenopausal females present the lowest mortality among adults infected by SARS-CoV-2. The goal of the present study was to investigate whet...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mavragani, Clio P., Skarlis, Charalampos, Kostopoulos, Ioannis V., Maratou, Eirini, Moutsatsou, Paraskevi, Terpos, Evangelos, Tsitsilonis, Ourania E., Dimopoulos, Meletios-Athanasios, Sfikakis, Petros P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Ltd. 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9289092/ https://www.ncbi.nlm.nih.gov/pubmed/35868117 http://dx.doi.org/10.1016/j.cyto.2022.155964

Ejemplares similares

Sjogren’s Syndrome: Recent Updates
por: Skarlis, Charalampos, et al.
Publicado: (2022)

Hematological Abnormalities in COVID-19 Disease: Association With Type I Interferon Pathway Activation and Disease Outcomes
por: Georgakopoulou, Vasiliki E., et al.
Publicado: (2022)

The Emerging Role of Convalescent Plasma in the Treatment of COVID-19
por: Psaltopoulou, Theodora, et al.
Publicado: (2020)

Milk Fat Globule Epidermal Growth Factor 8 (MFGE8) Gene Variants in Rheumatoid Arthritis and Sjögren’s Syndrome
por: Skarlis, Charalampos, et al.
Publicado: (2022)

Blood Transcriptomes of Anti-SARS-CoV-2 Antibody-Positive Healthy Individuals Who Experienced Asymptomatic Versus Clinical Infection
por: Sfikakis, Petros P., et al.
Publicado: (2021)

Peripheral Blood Immune Profiling of Convalescent Plasma Donors Reveals Alterations in Specific Immune Subpopulations Even at 2 Months Post SARS-CoV-2 Infection
por: Orologas-Stavrou, Nikolaos, et al.
Publicado: (2020)

Recovery of Innate Immune Cells and Persisting Alterations in Adaptive Immunity in the Peripheral Blood of Convalescent Plasma Donors at Eight Months Post SARS-CoV-2 Infection
por: Kostopoulos, Ioannis V., et al.
Publicado: (2021)

Ex Vivo Models Simulating the Bone Marrow Environment and Predicting Response to Therapy in Multiple Myeloma
por: Papadimitriou, Konstantinos, et al.
Publicado: (2020)

Study of the incidence of osteoporosis in patients with Sjögren’s syndrome (pSS) and investigation of activation of the RANKL /RANK and osteoprotegerin (OPG) system
por: Skarlis, Charalampos, et al.
Publicado: (2018)

Insights to SARS-CoV-2 life cycle, pathophysiology, and rationalized treatments that target COVID-19 clinical complications
por: Trougakos, Ioannis P., et al.
Publicado: (2021)

The Cytogenetic Profile of Primary and Secondary Plasma Cell Leukemia: Etiopathogenetic Perspectives, Prognostic Impact and Clinical Relevance to Newly Diagnosed Multiple Myeloma with Differential Circulating Clonal Plasma Cells
por: Papadhimitriou, Stefanos I., et al.
Publicado: (2022)

Atherosclerosis in SLE: a potential role for serum parathormone levels
por: Giannelou, Mayra, et al.
Publicado: (2020)

Systemic autoimmune diseases, anti-rheumatic therapies, COVID-19 infection risk and patient outcomes
por: Kastritis, Efstathios, et al.
Publicado: (2020)

Adverse effects of COVID-19 mRNA vaccines: the spike hypothesis
por: Trougakos, Ioannis P., et al.
Publicado: (2022)

Interleukin-1 Beta in Peripheral Blood Mononuclear Cell Lysates as a Longitudinal Biomarker of Response to Antidepressants: A Pilot Study
por: Ferentinos, Panagiotis, et al.
Publicado: (2021)

Differentiating central nervous system demyelinating disorders: The role of clinical, laboratory, imaging characteristics and peripheral blood type I interferon activity
por: Karathanasis, Dimitris K., et al.
Publicado: (2022)

Molecular responses to therapeutic proteasome inhibitors in multiple myeloma patients are donor-, cell type- and drug-dependent
por: Papanagnou, Eleni-Dimitra, et al.
Publicado: (2018)

Minimal Residual Disease in Multiple Myeloma: Current Landscape and Future Applications With Immunotherapeutic Approaches
por: Kostopoulos, Ioannis V., et al.
Publicado: (2020)

Persisting Endothelial Cell Activation and Hypercoagulability after Recovering from COVID-19: The Roadmap-Post COVID-19 Study
por: Van Dreden, Patrick, et al.
Publicado: (2022)

Osteoprotegerin and MTHFR gene variations in rheumatoid arthritis: association with disease susceptibility and markers of subclinical atherosclerosis
por: Arida, Aikaterini, et al.
Publicado: (2022)

+3179G/A Insulin-Like Growth Factor-1 Receptor Polymorphism: A Novel Susceptibility Contributor in Anti-Ro/SSA Positive Patients with Sjögren’s Syndrome: Potential Clinical and Pathogenetic Implications
por: Skarlis, Charalampos, et al.
Publicado: (2021)

Sequential Analysis of Binding and Neutralizing Antibody in COVID-19 Convalescent Patients at 14 Months After SARS-CoV-2 Infection
por: Rosati, Margherita, et al.
Publicado: (2021)

Convalescent plasma therapy in an immunocompromised patient with multiple COVID‐19 flares: a case report
por: Karaolidou, Frini, et al.
Publicado: (2021)

Convalescent Plasma Therapy for COVID-19: A Systematic Review and Meta-Analysis on Randomized Controlled Trials
por: Filippatos, Charalampos, et al.
Publicado: (2023)

Organ-specific manifestations of COVID-19 infection
por: Gavriatopoulou, Maria, et al.
Publicado: (2020)

The Role of Myositis-Specific and Myositis-Associated Autoantibodies and the Activation of Type I Interferon Pathway in the Generation of Clinical Phenotypes of Inflammatory Myopathies
por: Skarlis, Charalampos, et al.
Publicado: (2023)

Evaluation of minimal residual disease using next-generation flow cytometry in patients with AL amyloidosis
por: Kastritis, Efstathios, et al.
Publicado: (2018)

Seroprevalence of Antibodies against SARS-CoV-2 among the Personnel and Students of the National and Kapodistrian University of Athens, Greece: A Preliminary Report
por: Tsitsilonis, Ourania E., et al.
Publicado: (2020)

Chemotherapy resumption in ovarian cancer patient diagnosed with COVID-19
por: Liontos, Michalis, et al.
Publicado: (2020)

Cortisol and DHEAS in COVID-19
por: Yavropoulou, Maria P., et al.
Publicado: (2022)

SARS-CoV-2 Infection Is Asymptomatic in Nearly Half of Adults with Robust Anti-Spike Protein Receptor-Binding Domain Antibody Response
por: Tsitsilonis, Ourania E., et al.
Publicado: (2021)

The Compass-COVID19-ICU Study: Identification of Factors to Predict the Risk of Intubation and Mortality in Patients with Severe COVID-19
por: Van Dreden, Patrick, et al.
Publicado: (2021)

Kinetics of Nucleocapsid, Spike and Neutralizing Antibodies, and Viral Load in Patients with Severe COVID-19 Treated with Convalescent Plasma
por: Thomopoulos, Thomas P., et al.
Publicado: (2021)

COVID-19: Clinical features and outcomes in unvaccinated 2-dose and 3-dose vaccinated against SARS-CoV-2 patients with systemic autoimmune and autoinflammatory rheumatic diseases
por: Bakasis, Athanasios-Dimitrios, et al.
Publicado: (2022)

Emerging treatment strategies for COVID-19 infection
por: Gavriatopoulou, Maria, et al.
Publicado: (2020)

COVID-19 convalescent plasma
por: Tobian, Aaron A. R., et al.
Publicado: (2022)

Plasma nesfatin-1 and DDP-4 levels in patients with coronary artery disease: Kozani study
por: Kadoglou, Nikolaos P. E., et al.
Publicado: (2021)

COVID-19 mRNA vaccine-induced adverse effects: unwinding the unknowns
por: Trougakos, Ioannis P., et al.
Publicado: (2022)

SARS-CoV-2 antibody kinetics eight months from COVID-19 onset: Persistence of spike antibodies but loss of neutralizing antibodies in 24% of convalescent plasma donors
por: Terpos, Evangelos, et al.
Publicado: (2021)

Association Between DNA Damage Response, Fibrosis and Type I Interferon Signature in Systemic Sclerosis
por: Vlachogiannis, Nikolaos I., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_8s20spuhb6agkagtqdbq6iartu