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Bifidobacterium infantis Promotes Foxp3 Expression in Colon Cells via PD-L1-Mediated Inhibition of the PI3K-Akt-mTOR Signaling Pathway

AIM: Our objective was to investigate whether Bifidobacterium infantis inhibits PI3K-Akt-mTOR signaling and upregulates Foxp3 expression through PD-L1 and to explore the possible mechanism of action of B. infantis in cellular immunosuppression. METHOD: The effects of B. infantis supernatant on PD-L1...

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Detalles Bibliográficos
Autores principales: Zhou, Linyan, Xie, Ying, Li, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9289111/
https://www.ncbi.nlm.nih.gov/pubmed/35860248
http://dx.doi.org/10.3389/fimmu.2022.871705

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