Serum Derivatives of Reactive Oxygen Metabolites are Associated with Severity of Chronic Obstructive Pulmonary Disease and Affected by a p53 Gene Polymorphism

PURPOSE: Oxidative stress is known to activate tumor suppressor p53, which inhibits cell cycle progression and induces apoptosis. Levels of p53 in lung tissues from patients with chronic obstructive pulmonary disease (COPD) are increased compared with levels in nonsmokers or smokers without emphysem...

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Detalles Bibliográficos
Autores principales: Yamamura, Koichi, Nojiri, Masafumi, Nishiki, Kazuaki, Kato, Ryo, Shinomiya, Shohei, Takahara, Yutaka, Oikawa, Taku, Ishizaki, Takeshi, Toga, Hirohisa, Mizuno, Shiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9289177/
https://www.ncbi.nlm.nih.gov/pubmed/35854898
http://dx.doi.org/10.2147/COPD.S366792

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9289177/
https://www.ncbi.nlm.nih.gov/pubmed/35854898
http://dx.doi.org/10.2147/COPD.S366792

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