Evaluation of the Effects of Harmine on β-cell Function and Proliferation in Standardized Human Islets Using 3D High-Content Confocal Imaging and Automated Analysis

Restoration of β-cell mass through the induction of proliferation represents an attractive therapeutic approach for the treatment of diabetes. However, intact and dispersed primary islets suffer from rapidly deteriorating viability and function ex vivo, posing a significant challenge for their exper...

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Detalles Bibliográficos
Autores principales: Title, Alexandra C., Karsai, Maria, Mir-Coll, Joan, Grining, Özlem Yavas, Rufer, Chantal, Sonntag, Sebastian, Forschler, Felix, Jawurek, Sayro, Klein, Thomas, Yesildag, Burcak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9289187/
https://www.ncbi.nlm.nih.gov/pubmed/35860702
http://dx.doi.org/10.3389/fendo.2022.854094

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