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Intrathyroidal parathyroid carcinoma presenting as thyroid nodule: Case report of unusual location

INTRODUCTION: Parathyroid carcinoma (PC) is considered a rare and uncommon malignancy. Its prevalence is about 0.005% of all cancers. Intrathyroidal location is rare, rendering preoperative diagnosis tedious. Until now, around 700 cases of PC have been documented, reportedly, among them, less than 2...

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Autores principales: Said, Anajar, Abire, Allaoui, Soukaina, Laidi, Hind, Alatawna, Loubna, Taali, Ilias, Tahiri, Amal, Hajjij, Mustapha, Saadi, Mohammed, Zalakh, Fouad, Benariba
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9289316/
https://www.ncbi.nlm.nih.gov/pubmed/35860129
http://dx.doi.org/10.1016/j.amsu.2022.103994
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author Said, Anajar
Abire, Allaoui
Soukaina, Laidi
Hind, Alatawna
Loubna, Taali
Ilias, Tahiri
Amal, Hajjij
Mustapha, Saadi
Mohammed, Zalakh
Fouad, Benariba
author_facet Said, Anajar
Abire, Allaoui
Soukaina, Laidi
Hind, Alatawna
Loubna, Taali
Ilias, Tahiri
Amal, Hajjij
Mustapha, Saadi
Mohammed, Zalakh
Fouad, Benariba
author_sort Said, Anajar
collection PubMed
description INTRODUCTION: Parathyroid carcinoma (PC) is considered a rare and uncommon malignancy. Its prevalence is about 0.005% of all cancers. Intrathyroidal location is rare, rendering preoperative diagnosis tedious. Until now, around 700 cases of PC have been documented, reportedly, among them, less than 21 cases of intrathyroidal parathyroid carcinoma have been described in the literature. We report a case of intrathyroidal PC that was taken for a suspicious thyroid nodule, with a literature review. PRESENTATION OF THE CASE: Our case is an asymptomatic intrathyroidal PC imitating a suspicious thyroid nodule, in a 54-year-old woman. A literature review was performed about clinical, radiological features, histopathological findings, and therapeutic options. DISCUSSION: The diagnosis of asymptomatic intrathyroidal parathyroid carcinoma, similar to our case report, is even more difficult, our patient had no symptoms of hypercalcemia. Surgery is the cornerstone of the treatment. A better chance to cure this disease is conditioned by complete surgical resection with negative margins microscopically, that was the case of our patient with a very good clinical course after 12 months of follow-up.
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spelling pubmed-92893162022-07-19 Intrathyroidal parathyroid carcinoma presenting as thyroid nodule: Case report of unusual location Said, Anajar Abire, Allaoui Soukaina, Laidi Hind, Alatawna Loubna, Taali Ilias, Tahiri Amal, Hajjij Mustapha, Saadi Mohammed, Zalakh Fouad, Benariba Ann Med Surg (Lond) Case Report INTRODUCTION: Parathyroid carcinoma (PC) is considered a rare and uncommon malignancy. Its prevalence is about 0.005% of all cancers. Intrathyroidal location is rare, rendering preoperative diagnosis tedious. Until now, around 700 cases of PC have been documented, reportedly, among them, less than 21 cases of intrathyroidal parathyroid carcinoma have been described in the literature. We report a case of intrathyroidal PC that was taken for a suspicious thyroid nodule, with a literature review. PRESENTATION OF THE CASE: Our case is an asymptomatic intrathyroidal PC imitating a suspicious thyroid nodule, in a 54-year-old woman. A literature review was performed about clinical, radiological features, histopathological findings, and therapeutic options. DISCUSSION: The diagnosis of asymptomatic intrathyroidal parathyroid carcinoma, similar to our case report, is even more difficult, our patient had no symptoms of hypercalcemia. Surgery is the cornerstone of the treatment. A better chance to cure this disease is conditioned by complete surgical resection with negative margins microscopically, that was the case of our patient with a very good clinical course after 12 months of follow-up. Elsevier 2022-06-15 /pmc/articles/PMC9289316/ /pubmed/35860129 http://dx.doi.org/10.1016/j.amsu.2022.103994 Text en © 2022 Published by Elsevier Ltd on behalf of IJS Publishing Group Ltd. https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Said, Anajar
Abire, Allaoui
Soukaina, Laidi
Hind, Alatawna
Loubna, Taali
Ilias, Tahiri
Amal, Hajjij
Mustapha, Saadi
Mohammed, Zalakh
Fouad, Benariba
Intrathyroidal parathyroid carcinoma presenting as thyroid nodule: Case report of unusual location
title Intrathyroidal parathyroid carcinoma presenting as thyroid nodule: Case report of unusual location
title_full Intrathyroidal parathyroid carcinoma presenting as thyroid nodule: Case report of unusual location
title_fullStr Intrathyroidal parathyroid carcinoma presenting as thyroid nodule: Case report of unusual location
title_full_unstemmed Intrathyroidal parathyroid carcinoma presenting as thyroid nodule: Case report of unusual location
title_short Intrathyroidal parathyroid carcinoma presenting as thyroid nodule: Case report of unusual location
title_sort intrathyroidal parathyroid carcinoma presenting as thyroid nodule: case report of unusual location
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9289316/
https://www.ncbi.nlm.nih.gov/pubmed/35860129
http://dx.doi.org/10.1016/j.amsu.2022.103994
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