Transcription Factor RUNX3 Mediates Plasticity of ThGM Cells Toward Th1 Phenotype

GM-CSF-producing T helper (Th) cells play a crucial role in the pathogenesis of autoimmune diseases such as multiple sclerosis (MS). Recent studies have identified a distinct population of GM-CSF-producing Th cells, named ThGM cells, that also express cytokines TNF, IL-2, and IL-3, but lack expressi...

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Detalles Bibliográficos
Autores principales: Rasouli, Javad, Casella, Giacomo, Zhang, Weifeng, Xiao, Dan, Kumar, Gaurav, Fortina, Paolo, Zhang, Guang-Xian, Ciric, Bogoljub, Rostami, Abdolmohamad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9289370/
https://www.ncbi.nlm.nih.gov/pubmed/35860266
http://dx.doi.org/10.3389/fimmu.2022.912583

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9289370/
https://www.ncbi.nlm.nih.gov/pubmed/35860266
http://dx.doi.org/10.3389/fimmu.2022.912583

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