Cargando…

Perampanel as First Add-On Therapy in Patients with Focal-Onset Seizures in the FAME Trial: Post hoc Analyses of Efficacy and Safety Related to Maintenance Dose and Background Antiepileptic Drug Therapy

BACKGROUND AND PURPOSE: FAME (Fycompa(®) as first Add-on to Monotherapy in patients with Epilepsy; NCT02726074), a previously reported single-arm, phase IV study, showed that perampanel improved seizure control as first add-on to failed anti-seizure medication (ASM) monotherapy in 85 South Korean pa...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kim, Ji Hyun, Kim, Dong Wook, Lee, Sang Kun, Seo, Dae-Won, Lee, Ji Woong, Kim, Min Young, Lee, Sang Ahm
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Epilepsy Society 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9289376/ https://www.ncbi.nlm.nih.gov/pubmed/35910326 http://dx.doi.org/10.14581/jer.22003

Ejemplares similares

Perampanel as First Adjunctive Treatment in Patients with Focal-Onset Seizures in the FAME Study: Post hoc Analyses of Dose-Related Efficacy, Safety and Clinical Factors Associated with Response
por: Kim, Dong Wook, et al.
Publicado: (2022)

First add‐on perampanel for focal‐onset seizures: An open‐label, prospective study
por: Kim, Ji Hyun, et al.
Publicado: (2019)

Successful Treatment of Drug-Resistant Seizures Secondary to Ring 20 Mosaicism with Perampanel as an Add-On Antiepileptic Drug
por: Ling, Janet, et al.
Publicado: (2022)

Efficacy and safety of perampanel as early add-on therapy in Chinese patients with focal-onset seizures: a multicenter, open-label, single-arm study
por: Gao, Lehong, et al.
Publicado: (2023)

Seizure remission and improvement of neurological function in sialidosis with perampanel therapy
por: Hu, Su-Ching, et al.
Publicado: (2018)

Antiepileptic Drug Withdrawal after Surgery in Children with Focal Cortical Dysplasia: Seizure Recurrence and Its Predictors
por: Choi, Sun Ah, et al.
Publicado: (2019)

Efficacy and Tolerability of Perampanel as Adjunctive Therapy in Chinese Patients With Focal-Onset Seizures: An Observational, Prospective Study
por: Zhang, Ranran, et al.
Publicado: (2021)

Efficacy of perampanel as an adjunctive therapy in pediatric focal epilepsy
por: Zhang, Wei-Ran, et al.
Publicado: (2023)

Impact of perampanel on pharmacokinetics of concomitant antiepileptics in patients with partial‐onset seizures: pooled analysis of clinical trials
por: Majid, Oneeb, et al.
Publicado: (2016)

Add-on perampanel in Lance–Adams syndrome
por: Steinhoff, Bernhard J., et al.
Publicado: (2016)

Experimental re-evaluation of flunarizine as add-on antiepileptic therapy
por: Thakur, Anamika, et al.
Publicado: (2011)

Brivaracetam: a novel antiepileptic drug for focal-onset seizures
por: Stephen, Linda J., et al.
Publicado: (2017)

Evaluation of perampanel as monotherapy for focal seizures: Experience from open-label extension studies
por: Kwan, Patrick, et al.
Publicado: (2017)

An Evidence-Based Review On The Use Of Perampanel For The Treatment Of Focal-Onset Seizures In Pediatric Patients
por: Dozières-Puyravel, Blandine, et al.
Publicado: (2019)

Spotlight on perampanel in the management of seizures: design, development and an update on place in therapy
por: Faulkner, Michele A
Publicado: (2017)

Adverse Events During Perampanel Adjunctive Therapy in Intractable Epilepsy
por: Youn, Song Ee, et al.
Publicado: (2018)

Efficacy and Safety of Perampanel in Children with Drug-Resistant Focal-Onset Seizures: A Retrospective Review
por: Elmardenly, Ahmed, et al.
Publicado: (2023)

Efficacy, safety, and tolerability of adjunctive perampanel in patients from China with focal seizures or generalized tonic‐clonic seizures: Post hoc analysis of phase III double‐blind and open‐label extension studies
por: Weiping, Liao, et al.
Publicado: (2020)

Efficacy and safety of adjunctive perampanel in patients with focal seizures or generalized tonic‐clonic seizures: Post hoc analysis of Phase II and Phase III double‐blind and open‐label extension studies in India
por: Mehndiratta, Man M., et al.
Publicado: (2021)

Investigating Perampanel Antiepileptic Drug by DFT Calculations and SERS with Custom Spinning Cell
por: Villa, Nicolò Simone, et al.
Publicado: (2023)

Antiepileptic Drug Therapy for Status Epilepticus
por: Kim, Daeyoung, et al.
Publicado: (2021)

Cost-effectiveness of perampanel as an adjunctive treatment for uncontrolled focal seizures in pediatric patients: a Chinese perspective
por: Hu, Yani, et al.
Publicado: (2022)

Efficacy and safety of adjunctive perampanel 4 mg/d for the treatment of focal seizures: A pooled post hoc analysis of four randomized, double‐blind, phase III studies
por: Steinhoff, Bernhard J., et al.
Publicado: (2020)

Fame
Publicado: (1858)

Such Is Fame
Publicado: (1886)

Mechanisms Underlying Aggressive Behavior Induced by Antiepileptic Drugs: Focus on Topiramate, Levetiracetam, and Perampanel
por: Hansen, Cerine C., et al.
Publicado: (2018)

Perampanel as add-on therapy in epilepsies with known etiology: A single center experience with long-term follow-up
por: Nilo, Annacarmen, et al.
Publicado: (2020)

The efficacy and safety of adjunctive perampanel for the treatment of refractory focal‐onset seizures in patients with epilepsy: A meta‐analysis
por: Li, Yiming, et al.
Publicado: (2022)

Clinical Experience with Perampanel in Intractable Focal Epilepsy Over 12 Months of Follow-Up
por: Kim, Soo Yeon, et al.
Publicado: (2018)

Antiepileptic Drug Therapy in Patients with Drug-Resistant Epilepsy
por: Park, Kang Min, et al.
Publicado: (2019)

Antiepileptic Drug Selection According to Seizure Type in Adult Patients with Epilepsy
por: Kim, Hyeyun, et al.
Publicado: (2020)

Experience of perampanel monotherapy beyond initial titration to achieve seizure freedom in patients with focal‐onset seizures with newly diagnosed or currently untreated recurrent epilepsy: A post hoc analysis of the open‐label Study 342 (FREEDOM)
por: Husni, Ryan Edbert, et al.
Publicado: (2021)

Preliminary evidence about irritability in patients with epilepsy treated by perampanel as first add‐on therapy compared to levetiracetam and valproic acid
por: Liguori, Claudio, et al.
Publicado: (2019)

Oral Levetiracetam as Add-On Therapy in Refractory Neonatal Seizures
por: MOLLAMOHAMMADI, Mohsen, et al.
Publicado: (2018)

Experience of Low Dose Perampanel to Add-on in Glioma Patients with Levetiracetam-uncontrollable Epilepsy
por: CHONAN, Masashi, et al.
Publicado: (2020)

Perampanel as first add-on antiseizure medication: Italian consensus clinical practice statements
por: Bonanni, Paolo, et al.
Publicado: (2021)

The lab of fame
por: Antonella Del Rosso
Publicado: (2014)

Fame 2 /
Publicado: (1984)

Effect of clobazam as add-on antiepileptic drug in patients with epilepsy
por: Joshi, Rupa, et al.
Publicado: (2014)

Efficacy and safety of perampanel monotherapy in patients with focal‐onset seizures with newly diagnosed epilepsy or recurrence of epilepsy after a period of remission: The open‐label Study 342 (FREEDOM Study)
por: Yamamoto, Takamichi, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_i8t3421jite18f2i2pe7q99pot