Successful Treatment of Patient with Lennox-Gastaut Syndrome with Combination of Levetiracetam, Lamotrigine and Valproate after Failure of Corpus Callosotomy

Lennox-Gastaut syndrome (LGS) is a pharmacoresistant epileptic encephalopathy. Herein reported is a case of LGS that combination therapy with levetiracetam, lamotrigine and valproate culminated in control of all seizure types and resolution of epileptic discharges in electroencephalography. This cas...

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Autor principal: Farzi, Mohammad Amin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Epilepsy Society 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9289379/
https://www.ncbi.nlm.nih.gov/pubmed/35910328
http://dx.doi.org/10.14581/jer.22007
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author Farzi, Mohammad Amin
author_facet Farzi, Mohammad Amin
author_sort Farzi, Mohammad Amin
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description Lennox-Gastaut syndrome (LGS) is a pharmacoresistant epileptic encephalopathy. Herein reported is a case of LGS that combination therapy with levetiracetam, lamotrigine and valproate culminated in control of all seizure types and resolution of epileptic discharges in electroencephalography. This case indicates that logical combination therapy may provide seizure control and improvement of electroencephalographic pattern in patients with LGS even in cases at which epileptic surgery fails.
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spelling pubmed-92893792022-07-29 Successful Treatment of Patient with Lennox-Gastaut Syndrome with Combination of Levetiracetam, Lamotrigine and Valproate after Failure of Corpus Callosotomy Farzi, Mohammad Amin J Epilepsy Res Case Report Lennox-Gastaut syndrome (LGS) is a pharmacoresistant epileptic encephalopathy. Herein reported is a case of LGS that combination therapy with levetiracetam, lamotrigine and valproate culminated in control of all seizure types and resolution of epileptic discharges in electroencephalography. This case indicates that logical combination therapy may provide seizure control and improvement of electroencephalographic pattern in patients with LGS even in cases at which epileptic surgery fails. Korean Epilepsy Society 2022-06-30 /pmc/articles/PMC9289379/ /pubmed/35910328 http://dx.doi.org/10.14581/jer.22007 Text en Copyright © 2022 Korean Epilepsy Society https://creativecommons.org/licenses/by-nc/3.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/ (https://creativecommons.org/licenses/by-nc/3.0/) ) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Farzi, Mohammad Amin
Successful Treatment of Patient with Lennox-Gastaut Syndrome with Combination of Levetiracetam, Lamotrigine and Valproate after Failure of Corpus Callosotomy
title Successful Treatment of Patient with Lennox-Gastaut Syndrome with Combination of Levetiracetam, Lamotrigine and Valproate after Failure of Corpus Callosotomy
title_full Successful Treatment of Patient with Lennox-Gastaut Syndrome with Combination of Levetiracetam, Lamotrigine and Valproate after Failure of Corpus Callosotomy
title_fullStr Successful Treatment of Patient with Lennox-Gastaut Syndrome with Combination of Levetiracetam, Lamotrigine and Valproate after Failure of Corpus Callosotomy
title_full_unstemmed Successful Treatment of Patient with Lennox-Gastaut Syndrome with Combination of Levetiracetam, Lamotrigine and Valproate after Failure of Corpus Callosotomy
title_short Successful Treatment of Patient with Lennox-Gastaut Syndrome with Combination of Levetiracetam, Lamotrigine and Valproate after Failure of Corpus Callosotomy
title_sort successful treatment of patient with lennox-gastaut syndrome with combination of levetiracetam, lamotrigine and valproate after failure of corpus callosotomy
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9289379/
https://www.ncbi.nlm.nih.gov/pubmed/35910328
http://dx.doi.org/10.14581/jer.22007
work_keys_str_mv AT farzimohammadamin successfultreatmentofpatientwithlennoxgastautsyndromewithcombinationoflevetiracetamlamotrigineandvalproateafterfailureofcorpuscallosotomy

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